High incidence of tuberculin skin test conversion among HIV-infected individuals who have a favourable immunological response to highly active antiretroviral therapy

Enrico Girardi, Fabrizio Palmieri, Mauro Zaccarelli, Valerio Tozzi, Maria P. Trotta, Cinzia Selva, Pasquale Narciso, Nicola Petrosillo, Andrea Antinori, Giuseppe Ippolito

Research output: Contribution to journalArticle

Abstract

A total of 129 HIV-infected individuals who were tuberculin skin test (TST) negative in 1997 and started highly active antiretroviral therapy (HAART) after skin testing, received a second TST during 2000. Seven patients converted to a positive TST. In multivariate analysis, an increase in CD4 T lymphocyte count more than 200 × 106/l over baseline was significantly associated with TST conversion. TST should be repeated in TST-negative HIV-infected individuals who experience an immunological response to HAART.

Original languageEnglish
Pages (from-to)1976-1979
Number of pages4
JournalAIDS (London, England)
Volume16
Issue number14
DOIs
Publication statusPublished - Sep 27 2002

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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