High intensity focused ultrasound ablation of pancreatic neuroendocrine tumours: Report of two cases

Gianluigi Orgera, Miltiadis Krokidis, Lorenzo Monfardini, Guido Bonomo, Paolo Della Vigna, Nicola Fazio, Franco Orsi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We describe the use of ultrasound-guided high-intensity focused ultrasound (HIFU) for ablation of two pancreatic neuroendocrine tumours (NETs; insulinomas) in two inoperable young female patients. Both suffered from episodes of severe nightly hypoglycemia that was not efficiently controlled by medical treatment. After HIFU ablation, local disease control and symptom relief were achieved without postinterventional complications. The patients remained free of symptoms during 9-month follow-up. The lesions appeared to be decreased in volume, and there was decreased enhancing pattern in the multidetector computed tomography control (MDCT). HIFU is likely to be a valid alternative for symptoms control in patients with pancreatic NETs. However, currently the procedure should be reserved for inoperable patients for whom symptoms cannot be controlled by medical therapy.

Original languageEnglish
Pages (from-to)419-423
Number of pages5
JournalCardioVascular and Interventional Radiology
Volume34
Issue number2
DOIs
Publication statusPublished - Apr 2011

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High-Intensity Focused Ultrasound Ablation
Neuroendocrine Tumors
Insulinoma
Multidetector Computed Tomography
Hypoglycemia
Therapeutics

Keywords

  • Interventional Oncology
  • Interventional Radiology

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

High intensity focused ultrasound ablation of pancreatic neuroendocrine tumours : Report of two cases. / Orgera, Gianluigi; Krokidis, Miltiadis; Monfardini, Lorenzo; Bonomo, Guido; Della Vigna, Paolo; Fazio, Nicola; Orsi, Franco.

In: CardioVascular and Interventional Radiology, Vol. 34, No. 2, 04.2011, p. 419-423.

Research output: Contribution to journalArticle

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