High interlaboratory reproducibility of matrix-assisted laser desorption ionization-time of flight mass spectrometry-based species identification of nonfermenting bacteria

A. Mellmann, F. Bimet, C. Bizet, A. D. Borovskaya, R. R. Drake, U. Eigner, A. M. Fahr, Y. He, E. N. Ilina, M. Kostrzewa, T. Maier, L. Mancinelli, W. Moussaoui, G. Prévost, L. Putignani, C. L. Seachord, Y. W. Tang, D. Harmsen

Research output: Contribution to journalArticlepeer-review

Abstract

Matrix-assisted laser desorption ionization-time of flight mass spectrometry has emerged as a rapid, cost-effective alternative for bacterial species identification. Identifying 60 blind-coded nonfermenting bacteria samples, this international study (using eight laboratories) achieved 98.75% interlaboratory reproducibility. Only 6 of the 480 samples were misidentified due to interchanges (4 samples) or contamination (1 sample) or not identified because of insufficient signal intensity (1 sample).

Original languageEnglish
Pages (from-to)3732-3734
Number of pages3
JournalJournal of Clinical Microbiology
Volume47
Issue number11
DOIs
Publication statusPublished - Nov 2009

ASJC Scopus subject areas

  • Microbiology (medical)

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