High-level aminoglycoside resistance among enterococci: Evaluation of an agar screen susceptibility test

E. Nicastri, A. Tarasi, U. Visco Comandini, V. Gelfusa, R. Di Rosa, E. Di Rosa, M. Venditti, P. Serra

Research output: Contribution to journalArticle


Seventy-five enterococci from infected (63 isolates) and colonized (12 isolates) patients hospitalized in various divisions of the Policlinico Umberto I, University of Rome, were in vitro studied for high-level resistance (HLR) to gentamicin (HLRG) and streptomycin (HLRS) with adoption of a standard broth dilution and an agar screen test. The employed procedures provided equal results for 100% of the 75 isolates. Of these, 21 (28%) showed HLRG and 43 (57%) HLRS. Combined HLRG and HLRS were found in 18 (24%) isolates, whereas HLRS or HLRG alone were found in 25 (33%) and 3 (4%) isolates respectively. It is concluded that HLR to aminoglycosides may represent a major problem in Italian institutions. Along with other established procedures, the agar screen test employed in the study may be used to detect this antibiotic resistance in enterococci.

Original languageEnglish
Pages (from-to)9-11
Number of pages3
JournalJournal of Chemotherapy
Issue number1
Publication statusPublished - 1992


ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)

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