High level of hepatitis C endemicity in Gabon, equatorial Africa

Eric Delaporte, Valérie Thiers, Marie Christine Dazza, Raffaella Romeo, Najoua Mlika-Cabanne, Isabelle Aptel, Dirk Schrijvers, Christian Bréchet, Bernard Larouzé

Research output: Contribution to journalArticle

Abstract

To assess the prevalence of hepatitis C virus (HCV) infection, a community-based study was performed in eastern Gabon on 1172 subjects over 5 years of age. The prevalence of antibodies to HCV (anti-HCV) detected using second-generation enzyme-linked immunosorbent assay (elisa) and confirmed by an immunoblot assay (riba 2), was 6·5%. Anti-HCV prevalence increased with age but was related to neither sex nor ethnic group. Among 30 subjects with positive elisa results, 14 had HCV viraemia as shown by the polymerase chain reaction (11/12 riba positive, 2/15 riba negative, 1/3 riba indeterminate). We conclude that HCV is highly endemic in western equatorial Africa and that a high proportion of the population may be viraemic.

Original languageEnglish
Pages (from-to)636-637
Number of pages2
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume87
Issue number6
DOIs
Publication statusPublished - 1993

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Gabon
Hepatitis C
Hepacivirus
Enzyme-Linked Immunosorbent Assay
Western Africa
Hepatitis C Antibodies
Viremia
Virus Diseases
Ethnic Groups
Polymerase Chain Reaction
Population

ASJC Scopus subject areas

  • Parasitology
  • Medicine(all)

Cite this

Delaporte, E., Thiers, V., Dazza, M. C., Romeo, R., Mlika-Cabanne, N., Aptel, I., ... Larouzé, B. (1993). High level of hepatitis C endemicity in Gabon, equatorial Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene, 87(6), 636-637. https://doi.org/10.1016/0035-9203(93)90269-V

High level of hepatitis C endemicity in Gabon, equatorial Africa. / Delaporte, Eric; Thiers, Valérie; Dazza, Marie Christine; Romeo, Raffaella; Mlika-Cabanne, Najoua; Aptel, Isabelle; Schrijvers, Dirk; Bréchet, Christian; Larouzé, Bernard.

In: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 87, No. 6, 1993, p. 636-637.

Research output: Contribution to journalArticle

Delaporte, E, Thiers, V, Dazza, MC, Romeo, R, Mlika-Cabanne, N, Aptel, I, Schrijvers, D, Bréchet, C & Larouzé, B 1993, 'High level of hepatitis C endemicity in Gabon, equatorial Africa', Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 87, no. 6, pp. 636-637. https://doi.org/10.1016/0035-9203(93)90269-V
Delaporte, Eric ; Thiers, Valérie ; Dazza, Marie Christine ; Romeo, Raffaella ; Mlika-Cabanne, Najoua ; Aptel, Isabelle ; Schrijvers, Dirk ; Bréchet, Christian ; Larouzé, Bernard. / High level of hepatitis C endemicity in Gabon, equatorial Africa. In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 1993 ; Vol. 87, No. 6. pp. 636-637.
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