High-normal blood pressure impacts the right heart mechanics

A three-dimensional echocardiography and two-dimensional speckle tracking imaging study

Marijana Tadic, Cesare Cuspidi, Biljana Pencic, Aleksanda Sljivic, Branislava Ivanovic, Aleksandar Neskovic, Radisav Scepanovic, Vera Celic

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

OBJECTIVE: The aim of this study was to examine the relationship between increasing blood pressure (BP) and right ventricular (RV) and right atrial (RA) mechanics using two-dimensional echocardiography (2DE) strain analysis and three-dimensional echocardiography (3DE). METHODOLOGY: This cross-sectional study included 58 individuals with optimal BP, 57 individuals with high-normal BP, and 59 recently diagnosed untreated hypertensive patients of similar age and sex distribution. Data were analyzed according to 24-h systolic blood pressure values (cutoff values were 120 and 130 mmHg). All individuals underwent complete 2DE and 3DE examination. RESULTS: The global longitudinal RV strain decreased gradually from controls, to high-normal BP individuals, to hypertensive patients, whereas systolic and early diastolic strain rates were similar between high-normal BP and hypertensive patients, but decreased in comparison with optimal BP individuals. The same trend was observed for the global longitudinal RA strain and systolic and early diastolic strain rates. 3DE examination revealed that RV volumes were increased in hypertensive patients in comparison with optimal BP individuals, which resulted in a lower 3DE RV ejection fraction in hypertensive patients. Multivariate analysis showed that the RV wall thickness was the only echocardiographic parameter that was, in the same time, independently associated with global RV and RA strain, and RV diastolic function. CONCLUSION: The right heart deformation is significantly impaired in individuals with high-normal BP. This subclinical impairment of RV and RA mechanics and function in high-normal BP individuals seems to be similar to the impairment found in recently diagnosed hypertensive patients.

Original languageEnglish
Pages (from-to)145-152
Number of pages8
JournalBlood Pressure Monitoring
Volume19
Issue number3
DOIs
Publication statusPublished - 2014

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Three-Dimensional Echocardiography
Mechanics
Blood Pressure
Hypertension
Right Atrial Function
Right Ventricular Function
Sex Distribution
Age Distribution
Stroke Volume
Echocardiography
Multivariate Analysis
Cross-Sectional Studies

Keywords

  • high-normal blood pressure
  • hypertension
  • right ventricle
  • speckle tracking echocardiography
  • three-dimensional echocardiography

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine
  • Assessment and Diagnosis
  • Advanced and Specialised Nursing
  • Medicine(all)

Cite this

High-normal blood pressure impacts the right heart mechanics : A three-dimensional echocardiography and two-dimensional speckle tracking imaging study. / Tadic, Marijana; Cuspidi, Cesare; Pencic, Biljana; Sljivic, Aleksanda; Ivanovic, Branislava; Neskovic, Aleksandar; Scepanovic, Radisav; Celic, Vera.

In: Blood Pressure Monitoring, Vol. 19, No. 3, 2014, p. 145-152.

Research output: Contribution to journalArticle

Tadic, Marijana ; Cuspidi, Cesare ; Pencic, Biljana ; Sljivic, Aleksanda ; Ivanovic, Branislava ; Neskovic, Aleksandar ; Scepanovic, Radisav ; Celic, Vera. / High-normal blood pressure impacts the right heart mechanics : A three-dimensional echocardiography and two-dimensional speckle tracking imaging study. In: Blood Pressure Monitoring. 2014 ; Vol. 19, No. 3. pp. 145-152.
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