HIGH-PERFORMANCE LIGAND-EXCHANGE CHROMATOGRAPHY OF AMINO ACIDS ON CHIRAL STATIONARY PHASES.

V. Carunchio, A. Messina, M. Sinibaldi, S. Fanali

Research output: Contribution to journalArticle

Abstract

Three chiral stationary phases, obtained by grafting silica gel with (-)-trans-1,2-cyclohexanediamine, were studied for the resolution of alpha -amino acids by ligand-exchange chromatography. The packings were prepared by bonding the chiral ligand to silica gel via different hydrocarbon spacers. Separation of the optical isomers was accomplished by eluents containing a constant concentration of copper(II) acetate (0. 05mM). The elution sequence of amino acids was found to be dependent on the grafting reaction selected to prepare the chiral packings.

Original languageEnglish
Pages (from-to)401-404
Number of pages4
JournalHRC & CC. Journal of high resolution chromatography & chromatography communications
Volume11
Issue number5
Publication statusPublished - May 1988

ASJC Scopus subject areas

  • Engineering(all)

Fingerprint Dive into the research topics of 'HIGH-PERFORMANCE LIGAND-EXCHANGE CHROMATOGRAPHY OF AMINO ACIDS ON CHIRAL STATIONARY PHASES.'. Together they form a unique fingerprint.

  • Cite this