Abstract
The resolution of racemates on chiral chemically bonded silica gel by high-performance ligand-exchange chromatography is described. The stationary phase was prepared by bonding (-) trans 1,2 cyclohexanediamine to silica gel through the coupling agent 3-glycidoxypropyl silane. The resolution of several α-amino acids and of compounds of pharmaceutical interest is reported.
Original language | English |
---|---|
Pages (from-to) | 118-120 |
Number of pages | 3 |
Journal | Chromatographia |
Volume | 23 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb 1987 |
Keywords
- Amino acids
- Chiral bonded phase
- Column liquid chromatography
- Ligand-exchange chromatography
- Racemate resolution
ASJC Scopus subject areas
- Analytical Chemistry
- Clinical Biochemistry