High-performance liquid chromatographic resolution of enantiomers on chiral epoxy polymer-coated silica gel

A. Messina, I. Nicoletti, M. G. Quaglia-Strano, M. Sinibaldi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A chiral stationary phase for the separation of some D-and L-amino acid derivatives using a new resolving agent is described. The enantiomeric resolution was accomplished by normal phase high-performance liquid chromatography. The support was easily prepared by coating an epoxy polymer of L-valinamide on aminopropylsilanized macroporous silica. The influence of subambient temperatures on the enantioselectivity was also examined.

Original languageEnglish
Pages (from-to)477-480
Number of pages4
JournalChromatographia
Volume28
Issue number9-10
DOIs
Publication statusPublished - Nov 1989

Fingerprint

Enantiomers
Enantioselectivity
Silica Gel
High performance liquid chromatography
Silicon Dioxide
Polymers
High Pressure Liquid Chromatography
Derivatives
Amino Acids
Coatings
Temperature
Liquids

Keywords

  • Chiral stationary phase
  • Column liquid chromatography
  • Enantioseparation by HPLC
  • Resolution of amino acid derivatives

ASJC Scopus subject areas

  • Analytical Chemistry
  • Clinical Biochemistry

Cite this

High-performance liquid chromatographic resolution of enantiomers on chiral epoxy polymer-coated silica gel. / Messina, A.; Nicoletti, I.; Quaglia-Strano, M. G.; Sinibaldi, M.

In: Chromatographia, Vol. 28, No. 9-10, 11.1989, p. 477-480.

Research output: Contribution to journalArticle

Messina, A. ; Nicoletti, I. ; Quaglia-Strano, M. G. ; Sinibaldi, M. / High-performance liquid chromatographic resolution of enantiomers on chiral epoxy polymer-coated silica gel. In: Chromatographia. 1989 ; Vol. 28, No. 9-10. pp. 477-480.
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