TY - JOUR
T1 - High prevalence of acquired antimicrobial resistance unrelated to heavy antimicrobial consumption
AU - Bartoloni, Alessandro
AU - Bartalesi, Filippo
AU - Mantella, Antonia
AU - Dell'Amico, Emanuela
AU - Roselli, Mimmo
AU - Strohmeyer, Marianne
AU - Barahona, Herlan Gamboa
AU - Barrón, Virgilio Prieto
AU - Paradisi, Franco
AU - Rossolini, Gian Maria
PY - 2004/4/1
Y1 - 2004/4/1
N2 - In a very remote rural Bolivian community where the use of antimicrobials has been minimal and where exchanges with the exterior are very limited, 67% of subjects were found to be carriers of fecal Escherichia coli with acquired resistance to ≥1 antimicrobial agent(s); the highest rates were observed for tetracycline (64%), ampicillin (58%), trimethoprim-sulfamethoxazole (50%), and chloramphenicol (41%). The most relevant implication of these findings is that, in certain settings, the spread and maintenance of antimicrobial resistance can occur, regardless of whether selective pressure generated by the use of antimicrobials is present.
AB - In a very remote rural Bolivian community where the use of antimicrobials has been minimal and where exchanges with the exterior are very limited, 67% of subjects were found to be carriers of fecal Escherichia coli with acquired resistance to ≥1 antimicrobial agent(s); the highest rates were observed for tetracycline (64%), ampicillin (58%), trimethoprim-sulfamethoxazole (50%), and chloramphenicol (41%). The most relevant implication of these findings is that, in certain settings, the spread and maintenance of antimicrobial resistance can occur, regardless of whether selective pressure generated by the use of antimicrobials is present.
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U2 - 10.1086/382191
DO - 10.1086/382191
M3 - Article
C2 - 15031799
AN - SCOPUS:11144355722
VL - 189
SP - 1291
EP - 1294
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
SN - 0022-1899
IS - 7
ER -