High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotensin system in psoriatic patients.

P. Ena, P. Madeddu, N. Glorioso, D. Cerimele, A. Rappelli

Research output: Contribution to journalArticle

100 Citations (Scopus)

Abstract

We have observed a significant higher prevalence of essential hypertension, cardiovascular diseases and diabetes in a group of 100 psoriatic patients compared with sex and age matched hospitalized controls. Thirty-five psoriatic patients exhibited and enhanced plasma renin activity (PRA), while urinary aldosterone excretion was raised in 27% of the group. The autonomic responsiveness of psoriatic patients, studied by cold pressure test and tilting was normal; this finding supports the hypothesis that the enhanced activity of renin-angiotensin system is not due to an increased sympathetic function in these psoriatic patients. High values of cholesterol, triglycerides and depressed HDL-cholesterol concentrations were also observed. A complete clinical and laboratory examination is very useful in psoriasis in order to initiate an appropriate treatment of the risk factors whenever present.

Original languageEnglish
Pages (from-to)199-205
Number of pages7
JournalActa Cardiologica
Volume40
Issue number2
Publication statusPublished - 1985

Fingerprint

Renin-Angiotensin System
Cardiovascular Diseases
Aldosterone
Psoriasis
Renin
HDL Cholesterol
Triglycerides
Cholesterol
Pressure
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotensin system in psoriatic patients. / Ena, P.; Madeddu, P.; Glorioso, N.; Cerimele, D.; Rappelli, A.

In: Acta Cardiologica, Vol. 40, No. 2, 1985, p. 199-205.

Research output: Contribution to journalArticle

@article{e4345e603ff0451b8eb276e248dd3eb3,
title = "High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotensin system in psoriatic patients.",
abstract = "We have observed a significant higher prevalence of essential hypertension, cardiovascular diseases and diabetes in a group of 100 psoriatic patients compared with sex and age matched hospitalized controls. Thirty-five psoriatic patients exhibited and enhanced plasma renin activity (PRA), while urinary aldosterone excretion was raised in 27{\%} of the group. The autonomic responsiveness of psoriatic patients, studied by cold pressure test and tilting was normal; this finding supports the hypothesis that the enhanced activity of renin-angiotensin system is not due to an increased sympathetic function in these psoriatic patients. High values of cholesterol, triglycerides and depressed HDL-cholesterol concentrations were also observed. A complete clinical and laboratory examination is very useful in psoriasis in order to initiate an appropriate treatment of the risk factors whenever present.",
author = "P. Ena and P. Madeddu and N. Glorioso and D. Cerimele and A. Rappelli",
year = "1985",
language = "English",
volume = "40",
pages = "199--205",
journal = "Acta Cardiologica",
issn = "0001-5385",
publisher = "Acta Cardiologica",
number = "2",

}

TY - JOUR

T1 - High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotensin system in psoriatic patients.

AU - Ena, P.

AU - Madeddu, P.

AU - Glorioso, N.

AU - Cerimele, D.

AU - Rappelli, A.

PY - 1985

Y1 - 1985

N2 - We have observed a significant higher prevalence of essential hypertension, cardiovascular diseases and diabetes in a group of 100 psoriatic patients compared with sex and age matched hospitalized controls. Thirty-five psoriatic patients exhibited and enhanced plasma renin activity (PRA), while urinary aldosterone excretion was raised in 27% of the group. The autonomic responsiveness of psoriatic patients, studied by cold pressure test and tilting was normal; this finding supports the hypothesis that the enhanced activity of renin-angiotensin system is not due to an increased sympathetic function in these psoriatic patients. High values of cholesterol, triglycerides and depressed HDL-cholesterol concentrations were also observed. A complete clinical and laboratory examination is very useful in psoriasis in order to initiate an appropriate treatment of the risk factors whenever present.

AB - We have observed a significant higher prevalence of essential hypertension, cardiovascular diseases and diabetes in a group of 100 psoriatic patients compared with sex and age matched hospitalized controls. Thirty-five psoriatic patients exhibited and enhanced plasma renin activity (PRA), while urinary aldosterone excretion was raised in 27% of the group. The autonomic responsiveness of psoriatic patients, studied by cold pressure test and tilting was normal; this finding supports the hypothesis that the enhanced activity of renin-angiotensin system is not due to an increased sympathetic function in these psoriatic patients. High values of cholesterol, triglycerides and depressed HDL-cholesterol concentrations were also observed. A complete clinical and laboratory examination is very useful in psoriasis in order to initiate an appropriate treatment of the risk factors whenever present.

UR - http://www.scopus.com/inward/record.url?scp=0021903859&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021903859&partnerID=8YFLogxK

M3 - Article

VL - 40

SP - 199

EP - 205

JO - Acta Cardiologica

JF - Acta Cardiologica

SN - 0001-5385

IS - 2

ER -