High prevalence of qnr genes in commensal enterobacteria from healthy children in Peru and Bolivia

Lucia Pallecchi, Eleonora Riccobono, Antonia Mantella, Filippo Bartalesi, Samanta Sennati, Herlan Gamboa, Eduardo Gotuzzo, Alessandro Bartoloni, Gian Maria Rossolini

Research output: Contribution to journalArticlepeer-review

Abstract

A remarkable prevalence of qnrB (54%) and, at a lower level, of qnrS (14%) was discovered in pools of commensal enterobacteria from 310 healthy children living in Peru and Bolivia, using a metagenomic approach. Analysis of randomly selected enterobacterial pools revealed that qnrB was mainly carried by Escherichia coli and qnrS by Klebsiella pneumoniae. Investigation of 11 qnrB-positive isolates and 9 qnrS-positive isolates revealed the presence of plasmid-borne qnrB19 (n = 8), qnrB2 (n = 2), qnrB10 (n = 1), and qnrS1 (n = 9) genes.

Original languageEnglish
Pages (from-to)2632-2635
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume53
Issue number6
DOIs
Publication statusPublished - Jun 2009

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)
  • Pharmacology

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