High prevalence of simple kidney cysts in patients with primary hyperparathyroidism

S. Corbetta, C. Eller-Vainicher, L. Vicente, S. Carnicelli, F. Sardanelli, P. Beck-Peccoz, A. Spada

Research output: Contribution to journalArticlepeer-review

Abstract

PTH has been demonstrated to promote renal epithelial cell proliferation and cysts development. The study aimed to evaluate the prevalence of kidney cysts in patients with primary hyperparathyroidism (PHPT). The prevalence of renal cysts diagnosed at abdominal ultrasound examinations in 172 PHPT patients (59.4±15.1 yr, mean age±SD; female/male 2.8) with preserved renal function was compared with that observed in 210 age- and sex-matched healthy controls. All patients underwent clinical, serum, and urine evaluations, and bone mineralization assessment by dual X-ray absorptiometry. Simple kidney cysts occurred with a higher prevalence in both male and female PHPT patients in comparison with healthy controls (34.9% vs 16.2% p

Original languageEnglish
Pages (from-to)690-694
Number of pages5
JournalJournal of Endocrinological Investigation
Volume32
Issue number8
DOIs
Publication statusPublished - Sep 2009

Keywords

  • Hyperparathyroidism
  • Kidney cysts
  • PTH
  • TmP

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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