High prevalence of simple kidney cysts in patients with primary hyperparathyroidism

S. Corbetta; C. Eller-Vainicher; L. Vicente; S. Carnicelli; F. Sardanelli; P. Beck-Peccoz; A. Spada

doi:10.3275/6329

High prevalence of simple kidney cysts in patients with primary hyperparathyroidism

S. Corbetta, C. Eller-Vainicher, L. Vicente, S. Carnicelli, F. Sardanelli, P. Beck-Peccoz, A. Spada

Research output: Contribution to journal › Article › peer-review

Abstract

PTH has been demonstrated to promote renal epithelial cell proliferation and cysts development. The study aimed to evaluate the prevalence of kidney cysts in patients with primary hyperparathyroidism (PHPT). The prevalence of renal cysts diagnosed at abdominal ultrasound examinations in 172 PHPT patients (59.4±15.1 yr, mean age±SD; female/male 2.8) with preserved renal function was compared with that observed in 210 age- and sex-matched healthy controls. All patients underwent clinical, serum, and urine evaluations, and bone mineralization assessment by dual X-ray absorptiometry. Simple kidney cysts occurred with a higher prevalence in both male and female PHPT patients in comparison with healthy controls (34.9% vs 16.2% p

Original language	English
Pages (from-to)	690-694
Number of pages	5
Journal	Journal of Endocrinological Investigation
Volume	32
Issue number	8
DOIs	https://doi.org/10.3275/6329
Publication status	Published - Sep 2009

Keywords

Hyperparathyroidism
Kidney cysts
PTH
TmP

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

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10.3275/6329

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abstract = "PTH has been demonstrated to promote renal epithelial cell proliferation and cysts development. The study aimed to evaluate the prevalence of kidney cysts in patients with primary hyperparathyroidism (PHPT). The prevalence of renal cysts diagnosed at abdominal ultrasound examinations in 172 PHPT patients (59.4±15.1 yr, mean age±SD; female/male 2.8) with preserved renal function was compared with that observed in 210 age- and sex-matched healthy controls. All patients underwent clinical, serum, and urine evaluations, and bone mineralization assessment by dual X-ray absorptiometry. Simple kidney cysts occurred with a higher prevalence in both male and female PHPT patients in comparison with healthy controls (34.9% vs 16.2% p",

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AU - Corbetta, S.

AU - Eller-Vainicher, C.

AU - Vicente, L.

AU - Carnicelli, S.

AU - Sardanelli, F.

AU - Beck-Peccoz, P.

AU - Spada, A.

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AB - PTH has been demonstrated to promote renal epithelial cell proliferation and cysts development. The study aimed to evaluate the prevalence of kidney cysts in patients with primary hyperparathyroidism (PHPT). The prevalence of renal cysts diagnosed at abdominal ultrasound examinations in 172 PHPT patients (59.4±15.1 yr, mean age±SD; female/male 2.8) with preserved renal function was compared with that observed in 210 age- and sex-matched healthy controls. All patients underwent clinical, serum, and urine evaluations, and bone mineralization assessment by dual X-ray absorptiometry. Simple kidney cysts occurred with a higher prevalence in both male and female PHPT patients in comparison with healthy controls (34.9% vs 16.2% p

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High prevalence of simple kidney cysts in patients with primary hyperparathyroidism

Abstract

Keywords

ASJC Scopus subject areas

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