High proliferation rate in dystrophinopathies

G. Vita, G. Giuffrè, M. C. Monici, A. Toscano, G. Tuccari, [No Value] Neurologia

Research output: Contribution to journalArticlepeer-review


We investigated proliferation rate by the AgNOR method in muscle samples from 13 Duchenne (DMD), 9 Becker (BMD), 5 polymyositis (PM) patients and 10 normal subjects. Specimens were treated with a 25% silver nitrate solution, and the area occupied by silver dots (NORA, μ) in 200 nuclei per specimen was measured by image analysis. The mean NORA values encountered in DMD (4.327 ± 0.791), BMD (3.534 ± 0.312).and PM (3.781 ± 0.499) samples were significantly higher than that of normal muscle (1.682 ±0.288; p

Original languageEnglish
Pages (from-to)24
Number of pages1
JournalItalian Journal of Neurological Sciences
Issue number4
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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