High rate of oxacillin-resistant Staphylococcus aureus isolates in an Italian University Hospital

M. Venditti, P. Baiocchi, C. Brandimarte, A. Capone, C. Fimiani, C. Santini, A. Tarasi

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Abstract

We reviewed our routine clinical laboratory records from January 1990 to March 1993 to evaluate the rate of oxacillin-resistance among nosocomial isolates of Staphylococcus aureus. Of 265 clinically significant isolates, 174 (65%) were oxacillin-resistant S. aureus (ORSA). Most of these strains were obtained from surgery patients and/or were isolated from surgical wounds. The isolations of S. aureus increased during the study period: 45 in 1990, 50 in 1991, 130 in 1992 and 40 in the first trimester of 1993. The annual rates of ORSA among S. aureus isolated varied from 62 to 68% through these years. Most ORSA isolates proved resistant to ciprofloxacin, gentamicin and rifampicin, and susceptible to vancomycin, netilmicin and cotrimoxazole. Based on these results, the need for a stringent application of infection control measures is outlined.

Original languageEnglish
Pages (from-to)25-28
Number of pages4
JournalJournal of Chemotherapy
Volume6
Issue number1
Publication statusPublished - 1994

Keywords

  • antibiotic resistance
  • nosocomial infection
  • oxacillin-resistance
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)

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    Venditti, M., Baiocchi, P., Brandimarte, C., Capone, A., Fimiani, C., Santini, C., & Tarasi, A. (1994). High rate of oxacillin-resistant Staphylococcus aureus isolates in an Italian University Hospital. Journal of Chemotherapy, 6(1), 25-28.