High-sensitivity cardiac troponin T for detection of subtle abnormalities of cardiac phenotype in a general population of elderly individuals

S. Masson, R. Latini, G. F. Mureddu, N. Agabiti, M. Miceli, G. Cesaroni, F. Forastiere, U. H. Wienhues-Thelen, D. Block, C. Zaugg, T. Vago, A. Boccanelli

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To investigate the association between circulating cardiac biomarkers and minor abnormalities in cardiac phenotype [left ventricular (LV) mass and midwall fractional shortening (MFS)] in elderly individuals in a general population sample. Design and setting: We examined the relationship between plasma concentrations of high-sensitivity cardiac troponin T (hs-cTnT) or N-terminal probrain natriuretic peptide (NT-proBNP) and elevated LV mass (LV mass/body surface area >95 g m-2 for women and 115 g m-2 for men), reduced MFS (-1 vs. 4.6 [3.0-8.1] and 79 [41-151] ng L-1 respectively (P -1 for subjects with normal LV mass and mild, moderate or severe LV hypertrophy respectively (P 

Original languageEnglish
Pages (from-to)306-317
Number of pages12
JournalJournal of Internal Medicine
Volume273
Issue number3
DOIs
Publication statusPublished - Mar 2013

Keywords

  • Community
  • Elderly
  • Left ventricular mass
  • Midwall fractional shortening
  • Natriuretic peptide
  • Troponin

ASJC Scopus subject areas

  • Internal Medicine

Fingerprint

Dive into the research topics of 'High-sensitivity cardiac troponin T for detection of subtle abnormalities of cardiac phenotype in a general population of elderly individuals'. Together they form a unique fingerprint.

Cite this