Histochemical demonstration of heavy metals in the reptilian archicortex

Stefano Gozzo, Carmela Iacopino, Maria Concetta Altavista, Alberto Albanese

Research output: Contribution to journalArticlepeer-review


The topographic distribution of heavy metals has been studied in the reptilian brain by means of Timm's sulphide silver method. Timm-positive histochemical reaction was detected in the archicortex and in the septum. In the first region, the staining pattern yielded evidence of cortical layering and the distribution of mossy fiber terminals. In the septum, uneven distribution of histochemical staining permitted identification of different functional territories. These data show that the reptilian archicortex is in many ways homologous to the mammalian hippocampus and fascia dentata, and also indicate that it undergoes significant remodeling during evolution.

Original languageEnglish
Pages (from-to)11-19
Number of pages9
JournalInternational Journal of Neuroscience
Issue number1-2
Publication statusPublished - 1985


  • Cytoarchitectonics
  • Heavy metals
  • Hippocampal cortex
  • Histochemistry
  • Reptilian archicortex
  • Timm's method

ASJC Scopus subject areas

  • Neuroscience(all)

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