Histologic and ultrastructural findings of tissue ingrowth: The Leeds-Keio prosthetic anterior cruciate ligament

M. Marcacci, P. Gubellini, R. Buda, V. De Pasquale, R. Strocchi, A. P. Molgora, S. Zaffagnini, S. Guizzardi, A. Ruggeri

Research output: Contribution to journalArticlepeer-review

Abstract

A light and electron microscopy investigation was performed on a Leeds- Keio ligament removed because of rupture 18 months after implantation to repair an anterior cruciate ligament. The investigation showed fibrous connective tissue on the plane of the main stress force. There was elastin and adequate vascularization interspersed with Type I collagen fibrils in the area most distant from the ligament. The tissue near the Dacron fibers was highly cellular with a matrix of infrequent, thin collagen fibrils and abundant fine granular material. The growth of the host tissue occurred in and around a Leeds-Keio ligament in response to tensile stresses.

Original languageEnglish
Pages (from-to)115-121
Number of pages7
JournalClinical Orthopaedics and Related Research
Issue number267
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

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