Histological features of periprosthetic mammary capsules: Silicone vs. polyurethane

Franco Bassetto, Carlotta Scarpa, Elio Caccialanza, Maria Cristina Montesco, Patrizia Magnani

Research output: Contribution to journalArticlepeer-review


Background: Periprosthetic capsules are a common reaction of the body to silicone or polyurethane breast implants. The aim of this study was to evaluate similarities and differences in the histological features of periprosthetic capsules surrounding silicone implants and polyurethane foam-coated implants and to correlate those features with the age of the implants. Methods: Tissues were studied from 41 periprosthetic capsules surrounding textured prostheses and from 20 capsules surrounding polyurethane foam-coated implants. For each sample we evaluated synovial metaplasia, density of collagen fibers or fibrosis, orientation of collagen fibers, and foreign body reaction (granulomatous reaction). Results: Synovial metaplasia was seen in the capsular tissue from both types of implant, but more so from capsules surrounding polyurethane implants more than 5 years old. The density and orientation of the collagen fibers and the foreign body reaction were very similar for the two types of implant.

Original languageEnglish
Pages (from-to)481-485
Number of pages5
JournalAesthetic Plastic Surgery
Issue number4
Publication statusPublished - Aug 2010


  • Breast capsule
  • Collagen fibres
  • Foreign body reaction
  • Polyurethane implant
  • Silicone implant
  • Synovial metaplasia

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Histological features of periprosthetic mammary capsules: Silicone vs. polyurethane'. Together they form a unique fingerprint.

Cite this