Histology far away from Flatland: 3D roller-coasting into grade-dependent angiogenetic patterns in oligodendrogliomas: Images in Cellular/Molecular Medicine

P. Cassoni, L. Gaetano, R. Senetta, B. Bussolati, L. Molinaro, G. Bussolati

Research output: Contribution to journalArticlepeer-review

Abstract

Angiogenesis plays a key role in tumour progression, and undergoes structural changes associated to tumour biology itself. Although vessel density can be easily evaluated in brain tumours using a traditional immuno-histochemical approach, other parameters of conceptual/biological interest, such as the complex patterns of vascular growth, cannot be fully understood using a traditional bi-dimensional evaluation. We use here surgical specimens derived from oligodendrogliomas as a model for a novel elucidative 3D reconstruction of the grade-dependent vascular arborisation in brain tumours.

Original languageEnglish
Pages (from-to)564-568
Number of pages5
JournalJournal of Cellular and Molecular Medicine
Volume12
Issue number2
DOIs
Publication statusPublished - Apr 2008

Keywords

  • 3D
  • Angiogenesis
  • Oligodendroglioma

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

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