Histone hyperacetylation is induced in chick erythrocyte nuclei during reactivation in heterokaryons

Research output: Contribution to journalArticle

Abstract

Transcriptionally inactive avian red blood cell nuclei were reactivated by Sendai virus-induced fusion of chicken erythrocytes with HeLa cells. We have used antibodies which specifically recognize the tetraacetylated form of H4 histone to show that histone hyperacetylation is an event required for chromatin reorganization leading to a transcriptionally competent chromatin structure.

Original languageEnglish
Pages (from-to)25-30
Number of pages6
JournalExperimental Cell Research
Volume178
Issue number1
DOIs
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Cell Biology

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