In order to define correlations between histopathologic findings and timing of surgical treatment in 628 patients who underwent cholecystectomy for acute cholecystitis, a retrospective, from 1970 to 1977, and then prospective, from 1977 to 1990, analysis has been carried out. The results seem to suggest that early cholecystectomy, i.e. performed within 24-48 hours from disease onset, may represent the treatment of choice. To this timely measure should be attributed the favourable course of the disease; the evolution toward chronicity of the acute lesions most frequently encountered (acute suppurative, necrotic and purulent or hemorrhagic) resulting unlikely. On the other hand, perforation is particularly frequent among patients with acute cholecystitis submitted to delayed surgery, during the same admission (4.1%) or subsequently (4.2%), as well as among those who underwent emergency surgery for failure of the medical treatment (32.3%). Finally, advantages of early cholecystectomy are pointed out: easier surgical approach, lower postoperative morbility and mortality rate, shorter hospital stay.
|Translated title of the contribution||Histopathological aspects of acute cholecystitis: A further indication for early cholecystectomy|
|Number of pages||5|
|Publication status||Published - 1992|
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