Histopathological assessment in glossectomy: Harmonic shears versus monopolar electrosurgery pilot study

Giovanni Cristalli, Giuseppe Mercante, Renato Covello, Isabella Sperduti, Maria Paola Cristalli, Giuseppe Spriano

Research output: Contribution to journalArticlepeer-review


Objectives. The aim of the study was to gather information on outcomes and effect sizes of 2 surgical methods of glossectomy by using a grade system and an objective measure of artifacts in micrometers (mm). The collected data would be used to plan a definitive study. Study Design. Pilot study. Setting. Tertiary referral center. Material and Methods. Nineteen patients affected with tongue cancer were consecutively enrolled in a pilot study and treated by partial glossectomy. Eleven patients (57.89%) of group A were treated with monopolar electrocautery, while 8 patients (42.10%) of group B were treated with Harmonic Focus Curved Shears. Specimens were examined by a pathologist blinded to the surgical procedure, using a 4- grade system for margin artifact assessment (margin fragmentation, cautery/crush artifact, extravascular blood clot, capillary congestion) and for measuring artifact depth. Results. Artifact depth was more relevant in group A (765,633 mm) than in group B (473,939 mm). The difference between groups was significant at the 95% confidence interval (P

Original languageEnglish
Pages (from-to)1076-1082
Number of pages7
JournalOtolaryngology - Head and Neck Surgery
Issue number6
Publication statusPublished - Dec 2012


  • Electrocautery surgery
  • Glossectomy
  • Harmonic shears
  • Histology
  • Oral cavity
  • Tongue cancer

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery
  • Medicine(all)


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