Histopathological classification of nonantral gastric endocrine growths in man

Enrico Solcia, C. Bordi, W. Creutzfeldt, Y. Dayal, A. D. Dayan, S. Falkmer, L. Grimeliust, N. Havu

Research output: Contribution to journalArticle

320 Citations (Scopus)

Abstract

Recently, the gastric endocrine system has been recognized as the origin of benign and malignant tumors in pernicious anemia. It has also been found that the gastric endocrine cells respond to permanent elevation of serum gastrin levels induced by changes in acid secretion in response to surgical procedures, drug therapy and age. Therefore, a definition of nonantral gastric endocrine hyperplasia (simple or diffuse, linear or chain-forming, micronodular, adenomatoid), dysplasia (enlarging or fusing micronodules, microinvasion, nodular growth) and neoplasia (intramucosal carcinoid, invasive carcinoid) is presented. The individual entities are illustrated, together with the literature discussed and the techniques for their identification presented.

Original languageEnglish
Pages (from-to)185-200
Number of pages16
JournalDigestion
Volume41
Issue number4
DOIs
Publication statusPublished - 1988

Fingerprint

Stomach
Carcinoid Tumor
Growth
Pernicious Anemia
Endocrine System
Endocrine Cells
Gastrins
Hyperplasia
Neoplasms
Drug Therapy
Acids
Serum

Keywords

  • Argyrophilic cells
  • Carcinoidosis
  • ECL cell tumors
  • ECL cells
  • Gastric carcinoids
  • Gastric endocrine cells

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Solcia, E., Bordi, C., Creutzfeldt, W., Dayal, Y., Dayan, A. D., Falkmer, S., ... Havu, N. (1988). Histopathological classification of nonantral gastric endocrine growths in man. Digestion, 41(4), 185-200. https://doi.org/10.1159/000199786

Histopathological classification of nonantral gastric endocrine growths in man. / Solcia, Enrico; Bordi, C.; Creutzfeldt, W.; Dayal, Y.; Dayan, A. D.; Falkmer, S.; Grimeliust, L.; Havu, N.

In: Digestion, Vol. 41, No. 4, 1988, p. 185-200.

Research output: Contribution to journalArticle

Solcia, E, Bordi, C, Creutzfeldt, W, Dayal, Y, Dayan, AD, Falkmer, S, Grimeliust, L & Havu, N 1988, 'Histopathological classification of nonantral gastric endocrine growths in man', Digestion, vol. 41, no. 4, pp. 185-200. https://doi.org/10.1159/000199786
Solcia E, Bordi C, Creutzfeldt W, Dayal Y, Dayan AD, Falkmer S et al. Histopathological classification of nonantral gastric endocrine growths in man. Digestion. 1988;41(4):185-200. https://doi.org/10.1159/000199786
Solcia, Enrico ; Bordi, C. ; Creutzfeldt, W. ; Dayal, Y. ; Dayan, A. D. ; Falkmer, S. ; Grimeliust, L. ; Havu, N. / Histopathological classification of nonantral gastric endocrine growths in man. In: Digestion. 1988 ; Vol. 41, No. 4. pp. 185-200.
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