Histopathological evaluation for the prognosis of retinoblastoma

P. Tosi, M. Cintorino, P. Toti, V. Ninfo, M. C. Montesco, R. Frezzotti, T. Hadjistilianou, A. Acquaviva, P. Barbini

Research output: Contribution to journalArticle

Abstract

In the present study histologic, clinical and follow-up data of 37 cases of retinoblastoma were statistically analyzed by means of a multivariate method. The evaluated histological parameters were: growth pattern, degree of differentiation, number of mitoses, presence of necrosis, pseudorosettes, blood vessel basophilia, calcification, extension to anterior chamber, invasion of optic nerve and ocular coats (choroid and sclera). The analysis was based upon the Cox proportional hazards regression model. Invasion of ocular coats proved to be highly correlated to the prognosis (p

Original languageEnglish
Pages (from-to)173-177
Number of pages5
JournalOphthalmic Paediatrics and Genetics
Volume10
Issue number3
Publication statusPublished - 1989

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Retinoblastoma
Sclera
Choroid
Anterior Chamber
Optic Nerve
Proportional Hazards Models
Mitosis
Blood Vessels
Necrosis
Growth
Clinical Studies

ASJC Scopus subject areas

  • Genetics(clinical)
  • Ophthalmology
  • Pediatrics, Perinatology, and Child Health

Cite this

Tosi, P., Cintorino, M., Toti, P., Ninfo, V., Montesco, M. C., Frezzotti, R., ... Barbini, P. (1989). Histopathological evaluation for the prognosis of retinoblastoma. Ophthalmic Paediatrics and Genetics, 10(3), 173-177.

Histopathological evaluation for the prognosis of retinoblastoma. / Tosi, P.; Cintorino, M.; Toti, P.; Ninfo, V.; Montesco, M. C.; Frezzotti, R.; Hadjistilianou, T.; Acquaviva, A.; Barbini, P.

In: Ophthalmic Paediatrics and Genetics, Vol. 10, No. 3, 1989, p. 173-177.

Research output: Contribution to journalArticle

Tosi, P, Cintorino, M, Toti, P, Ninfo, V, Montesco, MC, Frezzotti, R, Hadjistilianou, T, Acquaviva, A & Barbini, P 1989, 'Histopathological evaluation for the prognosis of retinoblastoma', Ophthalmic Paediatrics and Genetics, vol. 10, no. 3, pp. 173-177.
Tosi P, Cintorino M, Toti P, Ninfo V, Montesco MC, Frezzotti R et al. Histopathological evaluation for the prognosis of retinoblastoma. Ophthalmic Paediatrics and Genetics. 1989;10(3):173-177.
Tosi, P. ; Cintorino, M. ; Toti, P. ; Ninfo, V. ; Montesco, M. C. ; Frezzotti, R. ; Hadjistilianou, T. ; Acquaviva, A. ; Barbini, P. / Histopathological evaluation for the prognosis of retinoblastoma. In: Ophthalmic Paediatrics and Genetics. 1989 ; Vol. 10, No. 3. pp. 173-177.
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