Hiv-1 and hiv-2 seroprevalence rates in mother-child pairs living in the gambia (West africa)

Annarosa Del Mistro; Jacques Chotard; Andrew J. Hall; Hilton Whittle; Anita De Rossi; Luigi Chieco-Bianchi

Hiv-1 and hiv-2 seroprevalence rates in mother-child pairs living in the gambia (West africa)

Annarosa Del Mistro, Jacques Chotard, Andrew J. Hall, Hilton Whittle, Anita De Rossi, Luigi Chieco-Bianchi

Istituto Oncologico Veneto

Research output: Contribution to journal › Article › peer-review

Abstract

Summary: A seroepidemiological study was conducted, during 1988 and 1989, of mother-child pairs living in The Gambia (West Africa) in order to determine the distribution of the human immunodeficiency viruses type 1 (HIV-1) and type 2 (HIV-2). Specimens were obtained from 931 children (age range, 14–17 months) and 923 mothers (age range, 14–47 years) using village-based cluster samples; the children are participating in The Gambia Hepatitis Intervention Study (GHIS), a large-scale HBV vaccination program. Large numbers of indeterminate Western blot patterns were observed among the mothers, mainly for HIV-1 antibodies; HIV-1 infected subjects were not found, whereas an HIV-2 seroprevalence rate of 0.75% was observed. The children born to the seven HIV-2 positive women were seronegative for HIV-2 antibodies, and none of the children showed HIV-2 or HIV-1 seropostitivity.

Original language	English
Pages (from-to)	19-24
Number of pages	6
Journal	Journal of Acquired Immune Deficiency Syndromes
Volume	5
Issue number	1
Publication status	Published - 1992

Keywords

HIV-1 and HIV-2 seroprevalence
The Gambia
Vertical transmission

ASJC Scopus subject areas

Infectious Diseases
Pharmacology (medical)
Virology
Immunology and Allergy

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title = "Hiv-1 and hiv-2 seroprevalence rates in mother-child pairs living in the gambia (West africa)",

abstract = "Summary: A seroepidemiological study was conducted, during 1988 and 1989, of mother-child pairs living in The Gambia (West Africa) in order to determine the distribution of the human immunodeficiency viruses type 1 (HIV-1) and type 2 (HIV-2). Specimens were obtained from 931 children (age range, 14–17 months) and 923 mothers (age range, 14–47 years) using village-based cluster samples; the children are participating in The Gambia Hepatitis Intervention Study (GHIS), a large-scale HBV vaccination program. Large numbers of indeterminate Western blot patterns were observed among the mothers, mainly for HIV-1 antibodies; HIV-1 infected subjects were not found, whereas an HIV-2 seroprevalence rate of 0.75% was observed. The children born to the seven HIV-2 positive women were seronegative for HIV-2 antibodies, and none of the children showed HIV-2 or HIV-1 seropostitivity.",

keywords = "HIV-1 and HIV-2 seroprevalence, The Gambia, Vertical transmission",

author = "Mistro, {Annarosa Del} and Jacques Chotard and Hall, {Andrew J.} and Hilton Whittle and Rossi, {Anita De} and Luigi Chieco-Bianchi",

year = "1992",

language = "English",

volume = "5",

pages = "19--24",

journal = "Journal of Acquired Immune Deficiency Syndromes",

issn = "1525-4135",

publisher = "Lippincott Williams and Wilkins",

number = "1",

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TY - JOUR

T1 - Hiv-1 and hiv-2 seroprevalence rates in mother-child pairs living in the gambia (West africa)

AU - Mistro, Annarosa Del

AU - Chotard, Jacques

AU - Hall, Andrew J.

AU - Whittle, Hilton

AU - Rossi, Anita De

AU - Chieco-Bianchi, Luigi

PY - 1992

Y1 - 1992

N2 - Summary: A seroepidemiological study was conducted, during 1988 and 1989, of mother-child pairs living in The Gambia (West Africa) in order to determine the distribution of the human immunodeficiency viruses type 1 (HIV-1) and type 2 (HIV-2). Specimens were obtained from 931 children (age range, 14–17 months) and 923 mothers (age range, 14–47 years) using village-based cluster samples; the children are participating in The Gambia Hepatitis Intervention Study (GHIS), a large-scale HBV vaccination program. Large numbers of indeterminate Western blot patterns were observed among the mothers, mainly for HIV-1 antibodies; HIV-1 infected subjects were not found, whereas an HIV-2 seroprevalence rate of 0.75% was observed. The children born to the seven HIV-2 positive women were seronegative for HIV-2 antibodies, and none of the children showed HIV-2 or HIV-1 seropostitivity.

AB - Summary: A seroepidemiological study was conducted, during 1988 and 1989, of mother-child pairs living in The Gambia (West Africa) in order to determine the distribution of the human immunodeficiency viruses type 1 (HIV-1) and type 2 (HIV-2). Specimens were obtained from 931 children (age range, 14–17 months) and 923 mothers (age range, 14–47 years) using village-based cluster samples; the children are participating in The Gambia Hepatitis Intervention Study (GHIS), a large-scale HBV vaccination program. Large numbers of indeterminate Western blot patterns were observed among the mothers, mainly for HIV-1 antibodies; HIV-1 infected subjects were not found, whereas an HIV-2 seroprevalence rate of 0.75% was observed. The children born to the seven HIV-2 positive women were seronegative for HIV-2 antibodies, and none of the children showed HIV-2 or HIV-1 seropostitivity.

KW - HIV-1 and HIV-2 seroprevalence

KW - The Gambia

KW - Vertical transmission

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