HIV-1 antibody serum negativity with urine positivity

H. B. Urnovitz, T. D. Gottfried, D. J. Robison, L. I. Lutwick, D. V. Lancers, L. Montagnier, M. Clerici, G. M. Shearer

Research output: Contribution to journalArticle

Abstract

7 individuals who were negative for HIV-1 antibody in a licensed serum enzyme immunoassay (EIA) were positive in a urine EIA and western blot (WB). Follow-up in individuals by use of a cell-mediated immune response showed 1 positive and 1 negative for HIV-1 peptide reactivity. In a second study, 4 out of 5 subjects positive by urine EIA and indeterminate or negative by serum WB were HIV-1 peptide positive in the cell-mediated immune test. Comparison of cell-mediated responses with urine antibody responses may help to resolve discrepant HIV-1 results. Lancet 1993; 342: 1458-59.

Original languageEnglish
Pages (from-to)1458-1459
Number of pages2
JournalLancet
Volume342
Issue number8885
DOIs
Publication statusPublished - Dec 11 1993

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Urnovitz, H. B., Gottfried, T. D., Robison, D. J., Lutwick, L. I., Lancers, D. V., Montagnier, L., Clerici, M., & Shearer, G. M. (1993). HIV-1 antibody serum negativity with urine positivity. Lancet, 342(8885), 1458-1459. https://doi.org/10.1016/0140-6736(93)92934-L