Sequenze provirali di HIV-1 nella saliva di soggetti con infezione da HIV.

Translated title of the contribution: HIV-1 proviral DNA sequences in the saliva of patients with HIV infection

M. Piazza, A. Chirianni, G. Liuzzi, P. Tullio Cataldo, G. Santoro, L. Barsanti, G. Batoni, L. Ceccherini Nelli

Research output: Contribution to journalArticlepeer-review

Abstract

In order to understand the significance of presence of HIV-1 in saliva, we searched for by PCR HIV-1 proviral sequences in the saliva cells of 49 HIV-1 infected patients. Seven out 49 specimens resulted positive, 4 of which were from patients with PGL, 1 with ARC and 2 with AIDS. Four patients had a CD4+ lymphocyte counts <200/cmm and in 3 patients the CD4+ lymphocyte count ranged from 200 to 400/cmm. Two patients were treated with AZT, 1 with DDI and 4 had no antiretroviral treatment. In conclusion, although HIV-1 proviral sequences have been found in saliva of HIV-1 infected patients, a larger group of patients should be investigated to define more precisely the role of HIV-1 in saliva.

Translated title of the contributionHIV-1 proviral DNA sequences in the saliva of patients with HIV infection
Original languageItalian
Pages (from-to)475-481
Number of pages7
JournalBollettino della Societa Italiana di Biologia Sperimentale
Volume68
Issue number7
Publication statusPublished - Jul 1992

ASJC Scopus subject areas

  • Medicine(all)

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