Sequenze provirali di HIV-1 nella saliva di soggetti con infezione da HIV.

M. Piazza; A. Chirianni; G. Liuzzi; P. Tullio Cataldo; G. Santoro; L. Barsanti; G. Batoni; L. Ceccherini Nelli

Sequenze provirali di HIV-1 nella saliva di soggetti con infezione da HIV.

Translated title of the contribution: HIV-1 proviral DNA sequences in the saliva of patients with HIV infection

M. Piazza, A. Chirianni, G. Liuzzi, P. Tullio Cataldo, G. Santoro, L. Barsanti, G. Batoni, L. Ceccherini Nelli

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article › peer-review

Abstract

In order to understand the significance of presence of HIV-1 in saliva, we searched for by PCR HIV-1 proviral sequences in the saliva cells of 49 HIV-1 infected patients. Seven out 49 specimens resulted positive, 4 of which were from patients with PGL, 1 with ARC and 2 with AIDS. Four patients had a CD4+ lymphocyte counts <200/cmm and in 3 patients the CD4+ lymphocyte count ranged from 200 to 400/cmm. Two patients were treated with AZT, 1 with DDI and 4 had no antiretroviral treatment. In conclusion, although HIV-1 proviral sequences have been found in saliva of HIV-1 infected patients, a larger group of patients should be investigated to define more precisely the role of HIV-1 in saliva.

Translated title of the contribution	HIV-1 proviral DNA sequences in the saliva of patients with HIV infection
Original language	Italian
Pages (from-to)	475-481
Number of pages	7
Journal	Bollettino della Societa Italiana di Biologia Sperimentale
Volume	68
Issue number	7
Publication status	Published - Jul 1992

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "Sequenze provirali di HIV-1 nella saliva di soggetti con infezione da HIV.",

abstract = "In order to understand the significance of presence of HIV-1 in saliva, we searched for by PCR HIV-1 proviral sequences in the saliva cells of 49 HIV-1 infected patients. Seven out 49 specimens resulted positive, 4 of which were from patients with PGL, 1 with ARC and 2 with AIDS. Four patients had a CD4+ lymphocyte counts <200/cmm and in 3 patients the CD4+ lymphocyte count ranged from 200 to 400/cmm. Two patients were treated with AZT, 1 with DDI and 4 had no antiretroviral treatment. In conclusion, although HIV-1 proviral sequences have been found in saliva of HIV-1 infected patients, a larger group of patients should be investigated to define more precisely the role of HIV-1 in saliva.",

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T1 - Sequenze provirali di HIV-1 nella saliva di soggetti con infezione da HIV.

AU - Piazza, M.

AU - Chirianni, A.

AU - Liuzzi, G.

AU - Tullio Cataldo, P.

AU - Santoro, G.

AU - Barsanti, L.

AU - Batoni, G.

AU - Ceccherini Nelli, L.

PY - 1992/7

Y1 - 1992/7

N2 - In order to understand the significance of presence of HIV-1 in saliva, we searched for by PCR HIV-1 proviral sequences in the saliva cells of 49 HIV-1 infected patients. Seven out 49 specimens resulted positive, 4 of which were from patients with PGL, 1 with ARC and 2 with AIDS. Four patients had a CD4+ lymphocyte counts <200/cmm and in 3 patients the CD4+ lymphocyte count ranged from 200 to 400/cmm. Two patients were treated with AZT, 1 with DDI and 4 had no antiretroviral treatment. In conclusion, although HIV-1 proviral sequences have been found in saliva of HIV-1 infected patients, a larger group of patients should be investigated to define more precisely the role of HIV-1 in saliva.

AB - In order to understand the significance of presence of HIV-1 in saliva, we searched for by PCR HIV-1 proviral sequences in the saliva cells of 49 HIV-1 infected patients. Seven out 49 specimens resulted positive, 4 of which were from patients with PGL, 1 with ARC and 2 with AIDS. Four patients had a CD4+ lymphocyte counts <200/cmm and in 3 patients the CD4+ lymphocyte count ranged from 200 to 400/cmm. Two patients were treated with AZT, 1 with DDI and 4 had no antiretroviral treatment. In conclusion, although HIV-1 proviral sequences have been found in saliva of HIV-1 infected patients, a larger group of patients should be investigated to define more precisely the role of HIV-1 in saliva.

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Sequenze provirali di HIV-1 nella saliva di soggetti con infezione da HIV.

Abstract

ASJC Scopus subject areas

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