Abstract
In order to understand the significance of presence of HIV-1 in saliva, we searched for by PCR HIV-1 proviral sequences in the saliva cells of 49 HIV-1 infected patients. Seven out 49 specimens resulted positive, 4 of which were from patients with PGL, 1 with ARC and 2 with AIDS. Four patients had a CD4+ lymphocyte counts <200/cmm and in 3 patients the CD4+ lymphocyte count ranged from 200 to 400/cmm. Two patients were treated with AZT, 1 with DDI and 4 had no antiretroviral treatment. In conclusion, although HIV-1 proviral sequences have been found in saliva of HIV-1 infected patients, a larger group of patients should be investigated to define more precisely the role of HIV-1 in saliva.
Translated title of the contribution | HIV-1 proviral DNA sequences in the saliva of patients with HIV infection |
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Original language | Italian |
Pages (from-to) | 475-481 |
Number of pages | 7 |
Journal | Bollettino della Societa Italiana di Biologia Sperimentale |
Volume | 68 |
Issue number | 7 |
Publication status | Published - Jul 1992 |
ASJC Scopus subject areas
- Medicine(all)