TY - JOUR
T1 - HIV and tuberculosis
T2 - The paradox of dual illnesses and the challenges of their fighting in the history
AU - Canetti, Diana
AU - Riccardi, Niccolò
AU - Martini, Mariano
AU - Villa, Simone
AU - Di Biagio, Antonio
AU - Codecasa, Luigi
AU - Castagna, Antonella
AU - Barberis, Ilaria
AU - Gazzaniga, Valentina
AU - Besozzi, Giorgio
N1 - Publisher Copyright:
© 2020
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/5
Y1 - 2020/5
N2 - Tuberculosis is an ancient infectious disease caused by the bacillus Mycobacterium tuberculosis that is still nowadays afflicting humans all over the world. It causes ill-health for 10 million people each year. Tuberculosis (TB) has been the leading cause of death from a single infectious agent, ranking above HIV/AIDS. In recent years, infection with HIV represents a major risk factor predisposing for infection and TB is the most common cause of AIDS-related death. Despite the treatment of HIV-associated TB has essentially retraced that recommended in HIV-negative cases, it has disclosed some additional challenges over the years. The association of delayed and missed diagnoses, logistic accidents and some well-known complications of HIV and TB treatment co-administration has contributed to 300,000 people living with HIV died from a preventable and curable disease like TB in 2017. The evaluation of new diagnostic and therapeutic approaches with the struggle to erase stigma are essential to successfully manage HIV-TB coinfection.
AB - Tuberculosis is an ancient infectious disease caused by the bacillus Mycobacterium tuberculosis that is still nowadays afflicting humans all over the world. It causes ill-health for 10 million people each year. Tuberculosis (TB) has been the leading cause of death from a single infectious agent, ranking above HIV/AIDS. In recent years, infection with HIV represents a major risk factor predisposing for infection and TB is the most common cause of AIDS-related death. Despite the treatment of HIV-associated TB has essentially retraced that recommended in HIV-negative cases, it has disclosed some additional challenges over the years. The association of delayed and missed diagnoses, logistic accidents and some well-known complications of HIV and TB treatment co-administration has contributed to 300,000 people living with HIV died from a preventable and curable disease like TB in 2017. The evaluation of new diagnostic and therapeutic approaches with the struggle to erase stigma are essential to successfully manage HIV-TB coinfection.
UR - http://www.scopus.com/inward/record.url?scp=85083693170&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85083693170&partnerID=8YFLogxK
U2 - 10.1016/j.tube.2020.101921
DO - 10.1016/j.tube.2020.101921
M3 - Review article
C2 - 32501257
AN - SCOPUS:85083693170
VL - 122
JO - Tuberculosis
JF - Tuberculosis
SN - 1472-9792
M1 - 101921
ER -