HIV, HCV and HBV: A Review of Parallels and Differences

Maria C. Leoni, Andrew Ustianowski, Hamzah Farooq, Joop E. Arends

Research output: Contribution to journalReview articlepeer-review

Abstract

Elimination of the three blood-borne viruses—human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV)—as public health issues may be plausible in the near future. Spectacular advances have been made with the introduction of highly effective antiviral agents into clinical practice, and prevention strategies are available for all three infections. Effective disease control, laid out by WHO global strategies, is currently feasible for all three viruses. However, for worldwide elimination of these viruses, effective vaccines are required that are currently only available for HBV. In this review differences and parallels among HIV, HCV and HBV will be discussed with a focus on virologic and therapeutic issues, and prospects for the future of HBV will be presented.

Original languageEnglish
Pages (from-to)407-419
Number of pages13
JournalInfectious Diseases and Therapy
Volume7
Issue number4
DOIs
Publication statusPublished - Dec 1 2018
Externally publishedYes

Keywords

  • Antiviral therapy
  • Elimination
  • Hepatitis B virus
  • Hepatitis C virus
  • HIV virus
  • Vaccination

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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