HIV/AIDS: Epidemic update, new treatment strategies and impact on autoimmunity

Francesco Croce, Stefania Piconi, Fabiola Atzeni, Piercarlo Sarzi-Puttini, Massimo Galli, Mario Clerici

Research output: Contribution to journalArticlepeer-review

Abstract

Human Immunodeficiency Virus (HIV) infection represents one of the most serious challenges to global public health, since more than 30 million people are living with HIV/AIDS worldwide. Highly active antiretroviral treatment (HAART) introduction has dramatically changed the mortality and morbidity of HIV-affected subjects in industrialized countries but has implied an evolution of many HIV-related aspects, both in the utilisation of new antiretroviral drugs options and in the newly-observed spectrum of HIV-associated diseases, including the rheumatic pathology. Current epidemiological, therapeutic, autoimmune and rheumatic aspects of HIV-1 infection are here discussed.

Original languageEnglish
JournalClinical and Experimental Rheumatology
Volume26
Issue number1 SUPPL. 48
Publication statusPublished - 2008

Keywords

  • Antiretroviral therapy
  • Autoimmunity
  • HIV
  • Lymphopenia

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

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