TY - JOUR
T1 - HIV/AIDS
T2 - Epidemic update, new treatment strategies and impact on autoimmunity
AU - Croce, Francesco
AU - Piconi, Stefania
AU - Atzeni, Fabiola
AU - Sarzi-Puttini, Piercarlo
AU - Galli, Massimo
AU - Clerici, Mario
PY - 2008
Y1 - 2008
N2 - Human Immunodeficiency Virus (HIV) infection represents one of the most serious challenges to global public health, since more than 30 million people are living with HIV/AIDS worldwide. Highly active antiretroviral treatment (HAART) introduction has dramatically changed the mortality and morbidity of HIV-affected subjects in industrialized countries but has implied an evolution of many HIV-related aspects, both in the utilisation of new antiretroviral drugs options and in the newly-observed spectrum of HIV-associated diseases, including the rheumatic pathology. Current epidemiological, therapeutic, autoimmune and rheumatic aspects of HIV-1 infection are here discussed.
AB - Human Immunodeficiency Virus (HIV) infection represents one of the most serious challenges to global public health, since more than 30 million people are living with HIV/AIDS worldwide. Highly active antiretroviral treatment (HAART) introduction has dramatically changed the mortality and morbidity of HIV-affected subjects in industrialized countries but has implied an evolution of many HIV-related aspects, both in the utilisation of new antiretroviral drugs options and in the newly-observed spectrum of HIV-associated diseases, including the rheumatic pathology. Current epidemiological, therapeutic, autoimmune and rheumatic aspects of HIV-1 infection are here discussed.
KW - Antiretroviral therapy
KW - Autoimmunity
KW - HIV
KW - Lymphopenia
UR - http://www.scopus.com/inward/record.url?scp=42549083388&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=42549083388&partnerID=8YFLogxK
M3 - Article
C2 - 18570754
AN - SCOPUS:42549083388
VL - 26
JO - Clinical and Experimental Rheumatology
JF - Clinical and Experimental Rheumatology
SN - 0392-856X
IS - 1 SUPPL. 48
ER -