HLA antigens and factor VIII antibody in classic hemophilia. European study group of factor VIII antibody

D. Frommel, J. P. Allain, E. Saint-Paul, C. Bosser, B. Noël, P. M. Mannucci, F. Pannicucci, M. Blombäck, O. Prou-Wartelle, J. Y. Muller

Research output: Contribution to journalArticlepeer-review

Abstract

Possible interrelations between the immune response factor VIII and the major histocompatibility system were investigated in 57 multi-transfused hemophilic brothers belonging to 26 families. Linkage appears very unlikely although formal proof of independence cannot be offered. The HLA system, therefore, does not provide markers predictive for the development of antibodies to factor VIII in severe hemophilia A.

Original languageEnglish
Pages (from-to)687-689
Number of pages3
JournalThrombosis and Haemostasis
Volume46
Issue number4
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Hematology

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