HLA-B*1819, a novel HLA-B allle identified by sequence-based typing

S. Frison, L. Crespiatico, E. Longhi, E. Guizzardi, F. Poli, M. Scalamogna

Research output: Contribution to journalArticle

Abstract

In this brief communication, we describe a novel human leukocyte antigen-B (HLA-B) allele (HLA-B*1819). This allele, found in an Italian Caucasian individual, differs from HLA-B*180101 by three nucleotide changes in exon 3. These mutations are located at positions 527, 538, and 539 where a T, a C, and a T are substituted respectively, by an A, a T, and a G, leading to three aminoacidic substitutions at codon 152 from Valine to Glutamic Acid (GTG→GAG), at codon 155 from Histidine to Glutamine (CAC→CAG), and at codon 156 from Cysteine to Tryptophan (TGT→TGG).

Original languageEnglish
Pages (from-to)592-594
Number of pages3
JournalTissue Antigens
Volume63
Issue number6
DOIs
Publication statusPublished - Jun 2004

Keywords

  • HLA
  • SBT

ASJC Scopus subject areas

  • Cell Biology
  • Immunology

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