HLA-DRB1 polymorphisms distribution in chronic dysimmune polyneuropathy

M. Gironi, F. R. Guerini, E. Beghi, G. Antonini, F. Martinelli-Boneschi, L. Ceresa, S. Morino, C. Agliardi, P. Ferrante, R. Nemni

Research output: Contribution to journalArticle

Abstract

The frequency of HLA-DRB1*15 polymorphism, which is strongly associated to multiple sclerosis, was investigated in 84 adult patients with chronic dysimmune polyneuropathy and 272 healthy controls. No significant differences were detected between cases and controls and, among patients, according to gender, peripheral nerve antigen antibody seropositivity, and electrophysiological features. A trend towards an increase of HLA-DRB1*11 in anti-MAG neuropathy was detected.

Original languageEnglish
Pages (from-to)967-969
Number of pages3
JournalNeuromuscular Disorders
Volume18
Issue number12
DOIs
Publication statusPublished - Dec 2008

Keywords

  • Anti-MAG neuropathies
  • Chronic inflammatory polyneuropathies
  • HLA polymorphisms
  • Peripheral nerve antibodies

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Genetics(clinical)
  • Neurology

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    Gironi, M., Guerini, F. R., Beghi, E., Antonini, G., Martinelli-Boneschi, F., Ceresa, L., Morino, S., Agliardi, C., Ferrante, P., & Nemni, R. (2008). HLA-DRB1 polymorphisms distribution in chronic dysimmune polyneuropathy. Neuromuscular Disorders, 18(12), 967-969. https://doi.org/10.1016/j.nmd.2008.07.008