HLA-G*0105N allele is associated with augmented risk for HIV infection in white female patients

Ludovica Segat, Eulalia Catamo, Annalisa Fabris, Marcello Morgutti, Pierlanfranco D'Agaro, Cesare Campello, Sergio Crovella

Research output: Contribution to journalArticle

Abstract

We analyzed HLA-G 3777G > C, HLA-G 14 bp deletion/insertion and HLA-G*0105N polymorphisms in HIV-positive white adult participants, infected through horizontal heterosexual transmission, and unexposed uninfected individuals, all from north eastern Italy. We report a new association between the HLA-G*0105N allele and HIV infection in adult white female participants, being HLA-G*0105N null allele correlated with an augmented risk (odds ratio = 4.35, 95% confidence interval = 1.38-18.07, P = 0.005) for HIV infection.

Original languageEnglish
Pages (from-to)1961-1964
Number of pages4
JournalAIDS (London, England)
Volume24
Issue number12
DOIs
Publication statusPublished - Jul 31 2010

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ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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