HLA gene frequencies and migration in an Italian province

A. De Silvestri; M. Martinetti; C. Daielli; L. Salvaneschi; M. Cuccia; C. R. Guglielmino

HLA gene frequencies and migration in an Italian province

A. De Silvestri, M. Martinetti, C. Daielli, L. Salvaneschi, M. Cuccia, C. R. Guglielmino

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

HLA class I (HLA-A, HLA-B) and class II (HLA-DR, HLA-DQ) gene frequencies in 6 subareas of Pavia province are calculated in two samples of bone marrow donors. We estimated the degree of genetic differentiation between the 6 sub-areas through the standardized variance F(ST). On the basis of the island migration model the number of migrants is estimated from F(ST) and compared with the observed migration index in the province according to the 1991 census.

Original language	English
Pages (from-to)	207-217
Number of pages	11
Journal	Gene Geography
Volume	10
Issue number	3
Publication status	Published - 1996

ASJC Scopus subject areas

Genetics(clinical)

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abstract = "HLA class I (HLA-A, HLA-B) and class II (HLA-DR, HLA-DQ) gene frequencies in 6 subareas of Pavia province are calculated in two samples of bone marrow donors. We estimated the degree of genetic differentiation between the 6 sub-areas through the standardized variance F(ST). On the basis of the island migration model the number of migrants is estimated from F(ST) and compared with the observed migration index in the province according to the 1991 census.",

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T1 - HLA gene frequencies and migration in an Italian province

AU - De Silvestri, A.

AU - Martinetti, M.

AU - Daielli, C.

AU - Salvaneschi, L.

AU - Cuccia, M.

AU - Guglielmino, C. R.

PY - 1996

Y1 - 1996

N2 - HLA class I (HLA-A, HLA-B) and class II (HLA-DR, HLA-DQ) gene frequencies in 6 subareas of Pavia province are calculated in two samples of bone marrow donors. We estimated the degree of genetic differentiation between the 6 sub-areas through the standardized variance F(ST). On the basis of the island migration model the number of migrants is estimated from F(ST) and compared with the observed migration index in the province according to the 1991 census.

AB - HLA class I (HLA-A, HLA-B) and class II (HLA-DR, HLA-DQ) gene frequencies in 6 subareas of Pavia province are calculated in two samples of bone marrow donors. We estimated the degree of genetic differentiation between the 6 sub-areas through the standardized variance F(ST). On the basis of the island migration model the number of migrants is estimated from F(ST) and compared with the observed migration index in the province according to the 1991 census.

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JO - Gene Geography

JF - Gene Geography

SN - 0394-249X

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ER -

HLA gene frequencies and migration in an Italian province

Abstract

ASJC Scopus subject areas

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