HLA typing does not predict REM sleep behaviour disorder and hallucinations in Parkinson's disease

Marco Onofrj, Ana Lisa Luciano, Diego Iacono, Astrid Thomas, Fabrizio Stocchi, Franco Papola, Domenico Adorno, Rocco Di Mascio

Research output: Contribution to journalArticlepeer-review

Abstract

HLA-DR2 haplotype and DQ1 DNA alleles, characterizing 90 to 100% of all narcoleptic patients, were found to be equally distributed in 20 Parkinson's disease (PD) patients with early hallucinations, rapid eye movement (REM) sleep-related behaviour disturbances (RBD), and sleep onset in REM (SOREM), and in 20 PD patients without hallucinations, despite 10 to 15 years of treatment, and no RBD or SOREM.

Original languageEnglish
Pages (from-to)337-340
Number of pages4
JournalMovement Disorders
Volume18
Issue number3
DOIs
Publication statusPublished - Mar 1 2003

Keywords

  • Hallucinations
  • HLA
  • Parkinson's disease
  • RBD

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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