HLA typing in 67 Italian patients with idiopathic hemochromatosis and their relatives

N. Panajotopoulos, A. Piperno, D. Conte, C. Mandelli, M. Cesana, F. Mercuriali, G. Fiorelli, P. A. Bianchi, S. Fargion

Research output: Contribution to journalArticlepeer-review

Abstract

The frequency of HLA A3 and B7 antigens was significantly higher in 67 unrelated patients with idiopathic hemochromatosis (IH) than in 700 controls (62.7% vs 22.5%, p-8 and 26.9% vs 9.3%, p-3, respectively). A3 B7, A3 B35 and A3 B5 were significantly more frequent in 72 haplotypes linked to IH gene than in 278 control haplotypes. The prevalence of B35 and A3 B35 was significantly higher in IH patients from North-Eastern Italy than from other regions (60% vs 21%, p

Original languageEnglish
Pages (from-to)431-436
Number of pages6
JournalTissue Antigens
Volume33
Issue number4
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Cell Biology
  • Immunology

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