Abstract
In the initial stages of cancer, tumor development and cell growth largely depend on external signals from the microenvironment. Inflammatory cells and soluble mediators such as cytokines and chemokines are the main microenvironmental factors that are involved in tumor cell migration and invasion, disease progression and angiogenesis. However, beyond these abnormalities, the relationships between lymphomas and their microenvironment appear to follow a pathogenetic pattern: an independent, largely autonomous pattern (Burkitt lymphoma); a pattern dependent on deregulated interactions (Hodgkin lymphoma); or a pattern dependent on regulated coexistence (HCV-associated marginal zone lymphomas and mucosa-associated lymphoid tissue lymphomas). This book is comprised of chapters written by distinguished authors from international academic institutions and cancer research centers, aiming to highlight the relevant role of the tumor microenvironment that has recently emerged in hematolymphoid malignancies. Volume 1 covers topics including microenvironment abnormalities, lymphoma proteomics, and the various treatment options currently available.
| Original language | English |
|---|---|
| Publisher | Future Medicine Ltd. |
| Number of pages | 140 |
| ISBN (Print) | 9781780845791, 9781780845814 |
| DOIs | |
| Publication status | Published - May 1 2015 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Hodgkin and non-hodgkin lymphomas seen through their microenvironment : Impact on diagnosis, prognosis and innovative therapy. / Carbone, Antonino; Younes, Anas.
Future Medicine Ltd., 2015. 140 p.Research output: Book/Report › Book
}
TY - BOOK
T1 - Hodgkin and non-hodgkin lymphomas seen through their microenvironment
T2 - Impact on diagnosis, prognosis and innovative therapy
AU - Carbone, Antonino
AU - Younes, Anas
PY - 2015/5/1
Y1 - 2015/5/1
N2 - In the initial stages of cancer, tumor development and cell growth largely depend on external signals from the microenvironment. Inflammatory cells and soluble mediators such as cytokines and chemokines are the main microenvironmental factors that are involved in tumor cell migration and invasion, disease progression and angiogenesis. However, beyond these abnormalities, the relationships between lymphomas and their microenvironment appear to follow a pathogenetic pattern: an independent, largely autonomous pattern (Burkitt lymphoma); a pattern dependent on deregulated interactions (Hodgkin lymphoma); or a pattern dependent on regulated coexistence (HCV-associated marginal zone lymphomas and mucosa-associated lymphoid tissue lymphomas). This book is comprised of chapters written by distinguished authors from international academic institutions and cancer research centers, aiming to highlight the relevant role of the tumor microenvironment that has recently emerged in hematolymphoid malignancies. Volume 1 covers topics including microenvironment abnormalities, lymphoma proteomics, and the various treatment options currently available.
AB - In the initial stages of cancer, tumor development and cell growth largely depend on external signals from the microenvironment. Inflammatory cells and soluble mediators such as cytokines and chemokines are the main microenvironmental factors that are involved in tumor cell migration and invasion, disease progression and angiogenesis. However, beyond these abnormalities, the relationships between lymphomas and their microenvironment appear to follow a pathogenetic pattern: an independent, largely autonomous pattern (Burkitt lymphoma); a pattern dependent on deregulated interactions (Hodgkin lymphoma); or a pattern dependent on regulated coexistence (HCV-associated marginal zone lymphomas and mucosa-associated lymphoid tissue lymphomas). This book is comprised of chapters written by distinguished authors from international academic institutions and cancer research centers, aiming to highlight the relevant role of the tumor microenvironment that has recently emerged in hematolymphoid malignancies. Volume 1 covers topics including microenvironment abnormalities, lymphoma proteomics, and the various treatment options currently available.
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U2 - 10.2217/9781780845791
DO - 10.2217/9781780845791
M3 - Book
AN - SCOPUS:84957043323
SN - 9781780845791
SN - 9781780845814
BT - Hodgkin and non-hodgkin lymphomas seen through their microenvironment
PB - Future Medicine Ltd.
ER -