Hodgkin lymphoma in patients with HIV infection

Michele Spina; Rosanna Ciancia; Accursio Augello; Massimiliano Berretta; Umberto Tirelli

doi:10.1007/978-1-4939-0859-2_17

Hodgkin lymphoma in patients with HIV infection

Michele Spina, Rosanna Ciancia, Accursio Augello, Massimiliano Berretta, Umberto Tirelli

Centro di Riferimento Oncologico

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Hodgkin lymphoma (HL) is a type of lymphoma characterized by Reed-Sternberg cells and often associated with systemic symptoms. While not considered an AIDS-defining malignancy, it is one of the more common non-AIDS-defining cancers. Most cases of HIV-associated HD are associated with Epstein-Barr virus. HD in persons infected with HIV tends to involve relatively unfavorable subtypes (mixed cellularity and lymphocyte), to be relatively more aggressive, and to more frequently exhibit extranodal involvement. Many of the cases of HIV-associated HD occur in patients with only moderate immunosuppression. Also, unlike most AIDS-related non-Hodgkin lymphoma, the incidence of HIV-associated HD has not decreased with the widespread use of HAART. In the era of highly active antiretroviral therapy (HAART) the same regimens employed in HIV-negative patients with HL can be used in HIV setting with similar results.

Original language	English
Title of host publication	Cancers in People with HIV and AIDS: Progress and Challenges
Publisher	Springer New York
Pages	235-243
Number of pages	9
ISBN (Print)	9781493908592, 1493908588, 9781493908585
DOIs	https://doi.org/10.1007/978-1-4939-0859-2_17
Publication status	Published - Mar 1 2014

ASJC Scopus subject areas

Medicine(all)
Immunology and Microbiology(all)

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AU - Ciancia, Rosanna

AU - Augello, Accursio

AU - Berretta, Massimiliano

AU - Tirelli, Umberto

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