Hodgkin's disease in HIV-infected individuals

Michele Spina, Simonetta Sandri, Umberto Tirelli

Research output: Contribution to journalArticlepeer-review

Abstract

The clinical and pathologic characteristics of Hodgkin's disease as they are diagnosed in patients with HIV infection differ from those of the general population. In fact, a higher frequency of unfavorable histologic subtypes, advanced stage, and poor therapeutic outcome have been reported in the HIV setting. Complete response rate after chemotherapy ranges from approximately 45% to 70%, although the disease-free survival is very short, and the median overall survival is only 18 months. The survival of these patients may be improved by the optimal combination of antineoplastic and antiretroviral treatment with the support of hematologic growth factors. However, new strategies of therapeutic intervention must be explored.

Original languageEnglish
Pages (from-to)522-526
Number of pages5
JournalCurrent Opinion in Oncology
Volume11
Issue number6
DOIs
Publication statusPublished - 1999

ASJC Scopus subject areas

  • Cancer Research

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