Holmium Laser Enucleation Versus Transurethral Resection of the Prostate: Results From a 2-Center Prospective Randomized Trial in Patients With Obstructive Benign Prostatic Hyperplasia

Francesco Montorsi, Richard Naspro, Andrea Salonia, Nazareno Suardi, Alberto Briganti, Matteo Zanoni, Sergio Valenti, Ivano Vavassori, Patrizio Rigatti

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To our knowledge we report the first multicenter, prospective, randomized study comparing holmium laser enucleation (HoLEP) and transurethral prostate resection (TURP) for obstructive benign prostatic hyperplasia. Materials and Methods: From January to October 2002, 100 consecutive patients with symptomatic obstructive benign prostatic hyperplasia were randomized at 2 centers to surgical treatment with HoLEP (52 in group 1) or TURP (48 in group 2). Patients in the 2 groups were preoperatively assessed by scoring subjective symptoms questionnaires. Preoperative and perioperative parameters were also evaluated, the latter at 1, 6 and 12 months of followup. Results: At baseline all patients had obstruction (Schäfer grade greater than 2). At the 1, 6 and 12-month followups no statistically significant differences were observed between the 2 groups in terms of urodynamic findings and subjective symptom scoring. In the HoLEP group mean total time in the operating room ± SD was significantly longer than for TURP (74 ± 19.5 vs 57 ± 15 minutes, p

Original languageEnglish
JournalJournal of Urology
Volume179
Issue number5 SUPPL.
DOIs
Publication statusPublished - May 2008

Keywords

  • laser surgery
  • prostate
  • prostatectomy
  • prostatic hyperplasia
  • transurethral resection of prostate

ASJC Scopus subject areas

  • Urology

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