Holmium laser enucleation versus transurethral resection of the prostate: Results from a 2-center, prospective, randomized trial in patients with obstructive benign prostatic hyperplasia

Francesco Montorsi, Richard Naspro, Andrea Salonia, Nazareno Suardi, Alberto Briganti, Matteo Zanoni, Sergio Valenti, Ivano Vavassori, Patrizio Rigatti

Research output: Contribution to journalArticle


Purpose: To our knowledge we report the first multicenter, prospective, randomized study comparing holmium laser enucleation (HoLEP) and transurethral prostate resection (TURP) for obstructive benign prostatic hyperplasia. Materials and Methods: From January to October 2002, 100 consecutive patients with symptomatic obstructive benign prostatic hyperplasia were randomized at 2 centers to surgical treatment with HoLEP (52 in group 1) or TURP (48 in group 2). Patients in the 2 groups were preoperatively assessed by scoring subjective symptoms questionnaires. Preoperative and perioperative parameters were also evaluated, the latter at 1, 6 and 12 months of followup. Results: At baseline all patients had obstruction (Schäfer grade greater than 2). At the 1, 6 and 12-month followups no statistically significant differences were observed between the 2 groups in terms of urodynamic findings and subjective symptom scoring. In the HoLEP group mean total time in the operating room ± SD was significantly longer than for TURP (74 ± 19.5 vs 57 ± 15 minutes, p

Original languageEnglish
Pages (from-to)1926-1929
Number of pages4
JournalJournal of Urology
Issue number5 I
Publication statusPublished - Nov 2004



  • Laser surgery
  • Prostate
  • Prostatectomy
  • Prostatic hyperplasia
  • Transurethral resection of prostate

ASJC Scopus subject areas

  • Urology

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