Holoprosencephaly in clomiphene-induced pregnancy: A possible association? A case report and literature review

G. Eleftheriou, R. Butera, L. Manzo

Research output: Contribution to journalArticlepeer-review

Abstract

Clomiphene is widely used for inducing ovulation. Evidence for congenital abnormalities, in particular central nervous system defects (CNS-D) and in babies born from clomiphene-induced pregnancies is conflicting. The authors report a case of holoprosencephalia (HPE) in a fetus delivered from a mother receiving clomiphene.

Original languageEnglish
Pages (from-to)535-536
Number of pages2
JournalClinical and Experimental Obstetrics and Gynecology
Volume39
Issue number4
Publication statusPublished - 2012

Keywords

  • Clomiphene
  • Holoprosencephaly
  • Malformation
  • Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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