Home and office uroflowmetry for evaluation of LUTS from benign prostatic enlargement

Daniele Porru, R. M. Scarpa, D. Prezioso, A. Bertaccini, C. A. Rizzi

Research output: Contribution to journalArticlepeer-review

Abstract

A group of 107 patients with lower urinary tract symptoms (LUTS) from benign prostatic enlargement (BPE) participated to the HOUSE Study (Home and Office Uroflowmetry Specific Evaluation). Patients received routine investigation, consisting of medical history taking, physical examination including digital rectal examination, prostate-specific antigen (PSA), assessment of symptoms listed both on the International Prostate Symptom Score and on ICS-male questionnaire. We examined the results of uroflowmetry evaluation in this population; data were analysed to observe if any circadian changes of parameters obtained with home uroflowmetry could be detected. We searched a correlation between Qmax, Qave and ICS-benign prostatic hyperplasia symptom score: a significantly inverse correlation was found only for Qmax, confirming Qmax as a reliable parameter to quantify subjective symptoms. When examining the multiple flow curves recorded in the same patient with home uroflowmetry, voided volume and flow time had usually higher values during night-time: the existence of circadian changes of uroflowmetry parameters in patients with LUTS from BPE was confirmed, and lower values of average and maximum flow rates during sleep hours were recorded in the same patient. In conclusion, when evaluating the natural history or treatment outcome of individual patients or group of patients in clinical trials for evaluation of BPE and LUTS, an assessment including multiple measurements may be useful and of value.

Original languageEnglish
Pages (from-to)45-49
Number of pages5
JournalProstate Cancer and Prostatic Diseases
Volume8
Issue number1
DOIs
Publication statusPublished - Mar 2005

Keywords

  • Benign prostatic hyperplasia
  • Bladder outflow obstruction
  • Home uroflowmetry
  • LUTS
  • Uroflowmetry

ASJC Scopus subject areas

  • Oncology
  • Urology

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