Home care for persons with AIDS: A case-control study to identify determinants of referral to a hospital-based scheme

G. Antonucci, E. Girardi, N. Orchi, C. A. Perucci, M. Fantoni, M. S. Aloisi, C. Del Borgo, G. Turbessi, A. Macedonio, G. Ippolito

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We conducted a multicenter, hospital-based case-control study to identify specific characteristics of AIDS patients which determine referral to hospital care at home. The cases were patients referred to a hospital-based home care scheme, in the metropolitan area of Rome, during 1997. Each case was matched with two controls. Social, demographic and clinical characteristics were collected at referral. Univariate and multivariate analysis were performed. In the study period, 119 cases and 238 controls were recruited. In logistic regression analysis, social characteristics were not found to affect referral to the hospital-at-home scheme. A severely impaired functional status - assessed by the Functional Independent Measure - identified by a score below 100 (Odds Ratio [OR] =15.2, 95% confidence interval [CI] 2.8-82.7), and the need for prolonged intravenous therapy (OR=12.4, 95% CI=3.3-46.3) were the only two independent predictors of home-care referral. We conclude that home care, even in a period when new potent combination antiretroviral therapies are widely available, is an important integrated service component for persons with AIDS with severe functional impairment or requiring intravenous therapy.

Original languageEnglish
Pages (from-to)322-328
Number of pages7
JournalJournal of Biological Regulators and Homeostatic Agents
Issue number3
Publication statusPublished - 2001


  • AIDS
  • Case-control study
  • Functional status
  • Home-care service
  • Hospital-at-home

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Endocrinology
  • Physiology
  • Immunology
  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Physiology (medical)


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