Homocysteine as an emerging risk factor for cardiovascular disease in the elderly

Betti Giusti, Anna Maria Gori, Rossella Marcucci, Claudia Saracini, Paola Bolli, Rosanna Abbate

Research output: Contribution to journalArticlepeer-review

Abstract

With longer average life expectancy, the prevalence of cardiovascular disease in later life is rising. A growing body of epidemiological evidence has shown a strong association between elevated homocysteine plasma levels and cardiovascular disease in the general population. This review focuses on the role of homocysteine as an emerging risk factor for cardiovascular disease in the elderly. The possibility of a relatively easy correction of hyperhomocysteinemia by vitamin supplementation represents an important stimulus to reach a definitive conclusion regarding the pathophysiological role of homocysteine as risk factor for cardiovascular disease in the general population and, in particular, elderly subjects.

Original languageEnglish
Pages (from-to)983-997
Number of pages15
JournalAging Health
Volume2
Issue number6
DOIs
Publication statusPublished - Dec 2006

Keywords

  • Aging
  • Cardiovascular disease
  • Cerebrovascular disease
  • Elderly
  • Homocysteine
  • Hyperhomocysteinemia
  • Inflammation
  • Risk factor

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Medicine(all)

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