Hormone-modulated rRNA gene activity is visualized by selective staining of the NOs

A. de Capoa, A. Baldini, P. Marlekaj, C. Natoli, M. Rocchi, N. Archidiacono, S. Cianfarani, G. L. Spadoni, B. Boscherini

Research output: Contribution to journalArticlepeer-review

Abstract

The role of Growth Hormone and Dexamethasone in the regulation of rRNA gene activity was evaluated on cultured human fibroblasts by the cytochemical method of selective silver staining. By this method the transcriptionally active r-gene clusters can be specifically visualized in individual cells. Statistically significant increases in the rate of rRNA transcriptional activity were demonstrated after hormone administration.

Original languageEnglish
Pages (from-to)791-796
Number of pages6
JournalCell Biology International Reports
Volume9
Issue number9
DOIs
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Cell Biology

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