Hospitalization for Charcot neuroarthropathy in diabetes: A population study in Italy

Roberto Anichini, Laura Policardo, Flavia Lucia Lombardo, Elisabetta Salutini, Anna Tedeschi, Secondina Viti, Piergiorgio Francia, Enrico Brocco, Marina Maggini, Giuseppe Seghieri, Alessandra De Bellis

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Aims To provide data on hospitalization and incidence rates of Charcot neuroarthropathy (CN) and its relation to lower limbs’ amputations/revascularizations in population with diabetes of Italy as well as of one of its regions (Tuscany). Methods Hospitalizations with CN diagnosis (codes ICD-9-CM: 7130, 7135, 7138) have been recorded in people with diabetes over years 2003–2013 in Italy and 2008–2015 in Tuscany. Amputations, peripheral vascular disease, revascularizations and infections were likewise evaluated. Results Between 2003 and 2013 CN hospitalizations were very infrequent in Italy ranging between 14 × 100,000 and 11 × 100,000 patients with diabetes. In Tuscany they declined to a minimum of 7 × 100,000 patients in 2015, after a previous increase to a maximum of 22 × 100,000 (p = NS for both). Yearly CN incidence remained constant in Italy, declining in Tuscany to a minimum of 3.4 × 100,000 diabetic patients in 2015 (p = 0.047). CN patients were younger and with longer length of hospital stay than those with non-Charcot diabetic foot (p < 0.05 for both). Amputation and infection rates were manifold higher in CN patients than in those with non-Charcot diabetic foot, while the revascularization rate was similar in both. Conclusions Over last decade, in Italy and Tuscany yearly CN incidence and hospitalization rates concerned only a small percentage of patients, remaining constant over years and declining in Tuscany in the last couple of years. CN was significantly associated to younger age, longer hospital stay and greater risk of amputations and infections while the need of revascularization was similar to that of non-Charcot diabetic foot.

Original languageEnglish
Pages (from-to)25-31
Number of pages7
JournalDiabetes Research and Clinical Practice
Volume129
DOIs
Publication statusPublished - Jul 1 2017

Fingerprint

Italy
Hospitalization
Amputation
Diabetic Foot
Population
Length of Stay
Incidence
Infection
Peripheral Vascular Diseases
International Classification of Diseases
Lower Extremity

Keywords

  • Amputations
  • Charcot neuroarthropathy
  • Diabetic foot
  • Hospitalization rate
  • Population study

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Anichini, R., Policardo, L., Lombardo, F. L., Salutini, E., Tedeschi, A., Viti, S., ... De Bellis, A. (2017). Hospitalization for Charcot neuroarthropathy in diabetes: A population study in Italy. Diabetes Research and Clinical Practice, 129, 25-31. https://doi.org/10.1016/j.diabres.2017.03.029

Hospitalization for Charcot neuroarthropathy in diabetes : A population study in Italy. / Anichini, Roberto; Policardo, Laura; Lombardo, Flavia Lucia; Salutini, Elisabetta; Tedeschi, Anna; Viti, Secondina; Francia, Piergiorgio; Brocco, Enrico; Maggini, Marina; Seghieri, Giuseppe; De Bellis, Alessandra.

In: Diabetes Research and Clinical Practice, Vol. 129, 01.07.2017, p. 25-31.

Research output: Contribution to journalArticle

Anichini, R, Policardo, L, Lombardo, FL, Salutini, E, Tedeschi, A, Viti, S, Francia, P, Brocco, E, Maggini, M, Seghieri, G & De Bellis, A 2017, 'Hospitalization for Charcot neuroarthropathy in diabetes: A population study in Italy', Diabetes Research and Clinical Practice, vol. 129, pp. 25-31. https://doi.org/10.1016/j.diabres.2017.03.029
Anichini, Roberto ; Policardo, Laura ; Lombardo, Flavia Lucia ; Salutini, Elisabetta ; Tedeschi, Anna ; Viti, Secondina ; Francia, Piergiorgio ; Brocco, Enrico ; Maggini, Marina ; Seghieri, Giuseppe ; De Bellis, Alessandra. / Hospitalization for Charcot neuroarthropathy in diabetes : A population study in Italy. In: Diabetes Research and Clinical Practice. 2017 ; Vol. 129. pp. 25-31.
@article{85a918156f754d2fa7e9ff718a4133b0,
title = "Hospitalization for Charcot neuroarthropathy in diabetes: A population study in Italy",
abstract = "Aims To provide data on hospitalization and incidence rates of Charcot neuroarthropathy (CN) and its relation to lower limbs’ amputations/revascularizations in population with diabetes of Italy as well as of one of its regions (Tuscany). Methods Hospitalizations with CN diagnosis (codes ICD-9-CM: 7130, 7135, 7138) have been recorded in people with diabetes over years 2003–2013 in Italy and 2008–2015 in Tuscany. Amputations, peripheral vascular disease, revascularizations and infections were likewise evaluated. Results Between 2003 and 2013 CN hospitalizations were very infrequent in Italy ranging between 14 × 100,000 and 11 × 100,000 patients with diabetes. In Tuscany they declined to a minimum of 7 × 100,000 patients in 2015, after a previous increase to a maximum of 22 × 100,000 (p = NS for both). Yearly CN incidence remained constant in Italy, declining in Tuscany to a minimum of 3.4 × 100,000 diabetic patients in 2015 (p = 0.047). CN patients were younger and with longer length of hospital stay than those with non-Charcot diabetic foot (p < 0.05 for both). Amputation and infection rates were manifold higher in CN patients than in those with non-Charcot diabetic foot, while the revascularization rate was similar in both. Conclusions Over last decade, in Italy and Tuscany yearly CN incidence and hospitalization rates concerned only a small percentage of patients, remaining constant over years and declining in Tuscany in the last couple of years. CN was significantly associated to younger age, longer hospital stay and greater risk of amputations and infections while the need of revascularization was similar to that of non-Charcot diabetic foot.",
keywords = "Amputations, Charcot neuroarthropathy, Diabetic foot, Hospitalization rate, Population study",
author = "Roberto Anichini and Laura Policardo and Lombardo, {Flavia Lucia} and Elisabetta Salutini and Anna Tedeschi and Secondina Viti and Piergiorgio Francia and Enrico Brocco and Marina Maggini and Giuseppe Seghieri and {De Bellis}, Alessandra",
year = "2017",
month = "7",
day = "1",
doi = "10.1016/j.diabres.2017.03.029",
language = "English",
volume = "129",
pages = "25--31",
journal = "Diabetes Research and Clinical Practice",
issn = "0168-8227",
publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Hospitalization for Charcot neuroarthropathy in diabetes

T2 - A population study in Italy

AU - Anichini, Roberto

AU - Policardo, Laura

AU - Lombardo, Flavia Lucia

AU - Salutini, Elisabetta

AU - Tedeschi, Anna

AU - Viti, Secondina

AU - Francia, Piergiorgio

AU - Brocco, Enrico

AU - Maggini, Marina

AU - Seghieri, Giuseppe

AU - De Bellis, Alessandra

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Aims To provide data on hospitalization and incidence rates of Charcot neuroarthropathy (CN) and its relation to lower limbs’ amputations/revascularizations in population with diabetes of Italy as well as of one of its regions (Tuscany). Methods Hospitalizations with CN diagnosis (codes ICD-9-CM: 7130, 7135, 7138) have been recorded in people with diabetes over years 2003–2013 in Italy and 2008–2015 in Tuscany. Amputations, peripheral vascular disease, revascularizations and infections were likewise evaluated. Results Between 2003 and 2013 CN hospitalizations were very infrequent in Italy ranging between 14 × 100,000 and 11 × 100,000 patients with diabetes. In Tuscany they declined to a minimum of 7 × 100,000 patients in 2015, after a previous increase to a maximum of 22 × 100,000 (p = NS for both). Yearly CN incidence remained constant in Italy, declining in Tuscany to a minimum of 3.4 × 100,000 diabetic patients in 2015 (p = 0.047). CN patients were younger and with longer length of hospital stay than those with non-Charcot diabetic foot (p < 0.05 for both). Amputation and infection rates were manifold higher in CN patients than in those with non-Charcot diabetic foot, while the revascularization rate was similar in both. Conclusions Over last decade, in Italy and Tuscany yearly CN incidence and hospitalization rates concerned only a small percentage of patients, remaining constant over years and declining in Tuscany in the last couple of years. CN was significantly associated to younger age, longer hospital stay and greater risk of amputations and infections while the need of revascularization was similar to that of non-Charcot diabetic foot.

AB - Aims To provide data on hospitalization and incidence rates of Charcot neuroarthropathy (CN) and its relation to lower limbs’ amputations/revascularizations in population with diabetes of Italy as well as of one of its regions (Tuscany). Methods Hospitalizations with CN diagnosis (codes ICD-9-CM: 7130, 7135, 7138) have been recorded in people with diabetes over years 2003–2013 in Italy and 2008–2015 in Tuscany. Amputations, peripheral vascular disease, revascularizations and infections were likewise evaluated. Results Between 2003 and 2013 CN hospitalizations were very infrequent in Italy ranging between 14 × 100,000 and 11 × 100,000 patients with diabetes. In Tuscany they declined to a minimum of 7 × 100,000 patients in 2015, after a previous increase to a maximum of 22 × 100,000 (p = NS for both). Yearly CN incidence remained constant in Italy, declining in Tuscany to a minimum of 3.4 × 100,000 diabetic patients in 2015 (p = 0.047). CN patients were younger and with longer length of hospital stay than those with non-Charcot diabetic foot (p < 0.05 for both). Amputation and infection rates were manifold higher in CN patients than in those with non-Charcot diabetic foot, while the revascularization rate was similar in both. Conclusions Over last decade, in Italy and Tuscany yearly CN incidence and hospitalization rates concerned only a small percentage of patients, remaining constant over years and declining in Tuscany in the last couple of years. CN was significantly associated to younger age, longer hospital stay and greater risk of amputations and infections while the need of revascularization was similar to that of non-Charcot diabetic foot.

KW - Amputations

KW - Charcot neuroarthropathy

KW - Diabetic foot

KW - Hospitalization rate

KW - Population study

UR - http://www.scopus.com/inward/record.url?scp=85019108358&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85019108358&partnerID=8YFLogxK

U2 - 10.1016/j.diabres.2017.03.029

DO - 10.1016/j.diabres.2017.03.029

M3 - Article

C2 - 28500867

AN - SCOPUS:85019108358

VL - 129

SP - 25

EP - 31

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

SN - 0168-8227

ER -