TY - JOUR
T1 - How and when investigating and treating helicobacter pylori infection in children
AU - Manfredi, Marco
AU - Gaiani, Federica
AU - Kayali, Stefano
AU - Bizzarri, Barbara
AU - Iuliano, Silvia
AU - Minelli, Roberta
AU - Leandro, Gioacchino
AU - Di Mario, Francesco
AU - De’angelis, Gian Luigi
PY - 2018/1/1
Y1 - 2018/1/1
N2 - For thousands of years humans have lived in symbiosis with Helicobacter pylori. This infection is acquired mainly during childhood and, despite it represents one of the most common infections in humans, only a minority of infected people may develop health issues and life-threatening diseases. For diagnosing Helicobacter pylori infection in children we can use, at first, non-invasive diagnostic tests, if clinical pattern and/or history are of suspicion. Then, invasive tests i.e. gastroscopy are necessary to confirm the infection. As antibiotics are not widely available in children affected by Helicobacter pylori infection, they should be chosen based on individual antibiotic susceptibility testing obtained by gastric biopsy specimens or the local antibiotic resistance pattern, in empirical treatment is chosen. Test and treat strategy in children should be avoided. In this brief review we summarize how and in which children the infection should be investigate and which the most appropriate eradication treatment should be chosen. (www.actabiomedica.it).
AB - For thousands of years humans have lived in symbiosis with Helicobacter pylori. This infection is acquired mainly during childhood and, despite it represents one of the most common infections in humans, only a minority of infected people may develop health issues and life-threatening diseases. For diagnosing Helicobacter pylori infection in children we can use, at first, non-invasive diagnostic tests, if clinical pattern and/or history are of suspicion. Then, invasive tests i.e. gastroscopy are necessary to confirm the infection. As antibiotics are not widely available in children affected by Helicobacter pylori infection, they should be chosen based on individual antibiotic susceptibility testing obtained by gastric biopsy specimens or the local antibiotic resistance pattern, in empirical treatment is chosen. Test and treat strategy in children should be avoided. In this brief review we summarize how and in which children the infection should be investigate and which the most appropriate eradication treatment should be chosen. (www.actabiomedica.it).
KW - Antibiotic resistance
KW - Antimicrobial susceptibility testing
KW - Children
KW - Esophagogastroduodenoscopy
KW - Helicobacter pylori
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U2 - 10.23750/abm.v89i8-S.7893
DO - 10.23750/abm.v89i8-S.7893
M3 - Review article
C2 - 30561420
AN - SCOPUS:85058771904
VL - 89
SP - 65
EP - 71
JO - Acta Biomedica de l'Ateneo Parmense
JF - Acta Biomedica de l'Ateneo Parmense
SN - 0392-4203
ER -